Results 31 to 40 of about 39,296 (293)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Due to increasing pressures on water resources, there is a need to monitor regional water resource availability in a spatially and temporally explicit manner.
Ate Poortinga +7 more
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Spatially varied open-channel flow equations [PDF]
Recent development and improvement in numerical techniques and computer capability enables more accurate numerical solutions of spatially varied flow problems such as various phases of urban storm runoffs.
Yen, Ben Chie
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
EFFECT OF DEM RESOLUTION ON LS FACTOR COMPUTATION [PDF]
LS factor plays a key role in soil erosion risk assessment using widely adopted empirical models such as RUSLE (Revised Universal Soil Loss Equation). The study was carried out to estimate the impact of varying DEM resolutions on LS factor values in a ...
A. R. Raj +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Improving Performance of Side Weirs Using Groups of Vane Plates or Piles [PDF]
Weirs are among the most common hydraulic structures that have been used for centuries by hydraulic engineers for flow measurement, energy dissipation, flow diversion, regulation of flow depth, and flood passage.
Abdorreza Kabiri-Samani +2 more
doaj
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

