Results 51 to 60 of about 964,237 (257)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

IMPROVING STUDENTS’ ENGLISH SPEAKING SKILL THROUGH CONTENT-BASED INSTRUCTION (A Classroom Action Research in the Second Grade Students of Business English Department of CsV&TC, China in the Academic Year of 2010/2011) [PDF]

open access: yes, 2011
The research is aimed at (1) finding whether and to what extent content-based instruction improved the students’ speaking skill; and (2) describing the teaching and learning situation when content-based instruction was applied in the speaking class ...
HUI, LI
core  

Skill of Speaking

open access: yes, 2023
Buku ini ditujukan untuk membantu para mahasiswa di dalam memahami hal-hal yang berkaitan dengan materi perkuliahan public speaking, serta memberikan gambaran mengenai kegiatan English speaking.
B, L. O. (La)   +3 more
core  

Speaking skill of elementary students reviewed by gender [PDF]

open access: yes, 2019
Speaking skill is one of language skill that used on daily life. Speaking skill include two aspects namely linguistic aspect and non-linguistic aspect. However, not all people have good speaking skill when facing some situation.
Cahyani, Isah   +2 more
core   +1 more source

Al-'Arabiyyah Baina Yadaik Book Speaking Skill Material Based On Common European Framework of Reference (CEFR)

open access: yesIzdihar, 2023
This research was conducted with the purpose of describing scope of speaking skill material including theme, functional competency, and types of text exercises and  describing level of speaking skill material in Al-‘Arabiyyah Baina Yadaik (ABY)  book ...
Muhammad Zahid 'Afifarrasyihab Rahimadinullah Samsudin   +3 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

IMPROVING STUDENTS’ WRITING SKILL USING A FOUR-PHASE TECHNIQUE [PDF]

open access: yes, 2012
This article describes a classroom action research held in writing class using a four-phase technique to improve the eleventh grade students’ writing skill and improve classroom situation.
Utami, Fitria Siti, Rais, A. Dahlan
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

SPEAKING SKILL ASSESSMENT INSTRUMENT DEVELOPMENT [PDF]

open access: yes, 2019
. This paper describes the idea of developing an instrument for assessing speaking skills in German speaking skill courses for beginners (Sprechfertigkeit für Anfänger).
Sari, Tanti Kurnia
core  

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