Results 91 to 100 of about 12,191,620 (284)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Developing a Teaching Collection of Manuscript Fragments at a Regional Comprehensive Institution
This essay shares the author's experiences of developing a teaching collection of medieval manuscript materials at a state school whose Special Collections library is relatively small, recently established, and modestly funded.
Kathryn R Vulic
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Objective – To measure the use of off-site storage for special collections materials and to examine how this use impacts core special collections activities. Design – Survey questionnaire containing both structured and open ended questions. Follow-up
Melissa Goertzen
doaj
On 7 February 2025, the National Commission for Special Libraries, Archives and Author Libraries, together with the AIB section Campania and the Library of the Agricultural Area of the University of Naples Federico II, promoted the study day Nuovi ...
Tania Maio
doaj +1 more source
Academic Special Collections and the Myths of Copyright
This study compares the copyright and use policy statements posted on the websites of the special collections of Association of Research Libraries member libraries.
Teresa Auch Schultz, Dana Miller
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The Impact of Off-Site Storage on Core Special Collections Activities
A Review of: Priddle, C., & McCann, L. (2015). Off-site storage and special collections: A study in use and impact in ARL libraries in the United States. College & Research Libraries, 76(5), 652-670.
Melissa Goertzen
doaj +1 more source
Special collections for beginners
Purpose – This article sets out to describe the challenges and opportunities created by the presentation of a number of special collections to the library service of Waterford Institute of Technology. It aims to focus on the work done with the collections to date and plans for the future.
Hayden, Helen, Darbey, Neil
openaire +2 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source

