Results 91 to 100 of about 12,191,620 (284)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Developing a Teaching Collection of Manuscript Fragments at a Regional Comprehensive Institution

open access: yesNew Chaucer Studies
This essay shares the author's experiences of developing a teaching collection of medieval manuscript materials at a state school whose Special Collections library is relatively small, recently established, and modestly funded.
Kathryn R Vulic
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Planning, Coordinating, and Managing Off-Site Storage is an Area of Increasing, Professional Responsibility for Special Collections Departments

open access: yesEvidence Based Library and Information Practice, 2016
Objective – To measure the use of off-site storage for special collections materials and to examine how this use impacts core special collections activities. Design – Survey questionnaire containing both structured and open ended questions. Follow-up
Melissa Goertzen
doaj  

«Trusted stewards of cultural heritage materials». Special collections processing skills in light of the study day “Nuovi strumenti per le collezioni speciali: dalle linee guida IFLA alle alle realtà professionali”

open access: yesBibliothecae.it
On 7 February 2025, the National Commission for Special Libraries, Archives and Author Libraries, together with the AIB section Campania and the Library of the Agricultural Area of the University of Naples Federico II, promoted the study day Nuovi ...
Tania Maio
doaj   +1 more source

Academic Special Collections and the Myths of Copyright

open access: yesJournal of Copyright in Education and Librarianship, 2019
This study compares the copyright and use policy statements posted on the websites of the special collections of Association of Research Libraries member libraries.
Teresa Auch Schultz, Dana Miller
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The Impact of Off-Site Storage on Core Special Collections Activities

open access: yesEvidence Based Library and Information Practice, 2016
A Review of: Priddle, C., & McCann, L. (2015). Off-site storage and special collections: A study in use and impact in ARL libraries in the United States. College & Research Libraries, 76(5), 652-670.
Melissa Goertzen
doaj   +1 more source

Special collections for beginners

open access: yesNew Library World, 2008
Purpose – This article sets out to describe the challenges and opportunities created by the presentation of a number of special collections to the library service of Waterford Institute of Technology. It aims to focus on the work done with the collections to date and plans for the future.
Hayden, Helen, Darbey, Neil
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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