Results 71 to 80 of about 896,807 (281)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

DiSCmap : digitisation of special collections mapping, assessment, prioritisation. Final project report [PDF]

open access: yes, 2009
Traditionally, digitisation has been led by supply rather than demand. While end users are seen as a priority they are not directly consulted about which collections they would like to have made available digitally or why.
Birrell, Duncan   +5 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

«Trusted stewards of cultural heritage materials». Special collections processing skills in light of the study day “Nuovi strumenti per le collezioni speciali: dalle linee guida IFLA alle alle realtà professionali”

open access: yesBibliothecae.it
On 7 February 2025, the National Commission for Special Libraries, Archives and Author Libraries, together with the AIB section Campania and the Library of the Agricultural Area of the University of Naples Federico II, promoted the study day Nuovi ...
Tania Maio
doaj   +1 more source

BIBLIOTECA FANTASMA, RECONSTRUCCIÓN VIRTUAL Y CONOCIMIENTOS COLONIALES. TRANSMUTACIONES DE LA BIBLIOTECA PERSONAL DEL ILUSTRADO AMERICANO MANUEL DEL SOCORRO RODRÍGUEZ

open access: yesCuadernos de Ilustración y Romanticismo, 2017
This article is a product of a research associated with the constitution of the Manuel del Socorro Rodríguez Special Collection in the National Library of Colombia.
Kevin Sedeño-Gullén
doaj   +1 more source

Special Collections Roadshow — Episode Ten: Union Uniform

open access: yes, 2016
Special Collections Roadshow was created by the Civil War Institute at Gettysburg College in the Spring of 2014. It normally showcases various artifacts from Special Collections at Gettysburg College.
McNish, Megan E., Sutter, Meg A.
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Planning, Coordinating, and Managing Off-Site Storage is an Area of Increasing, Professional Responsibility for Special Collections Departments

open access: yesEvidence Based Library and Information Practice, 2016
Objective – To measure the use of off-site storage for special collections materials and to examine how this use impacts core special collections activities. Design – Survey questionnaire containing both structured and open ended questions. Follow-up
Melissa Goertzen
doaj  

The status of photographs as library materials and their cataloguing through the perspective of Slovenian handbooks, reg

open access: yesKnjižnica, 2004
The article presents an overview of Slovene handbooks, regulations and standards, which are, or have been, used in the cataloguing of library materials. The research is concentrated on their relation with photographic materials ie. with the smallest part,
Branka Kerec
doaj   +1 more source

Special Collections Roadshow – Episode 9: Medical Kit

open access: yes, 2016
For our ninth episode we welcome our guest Dr. Ian Isherwood ’00 to talk about a Civil War medical kit and how to do research relating to Civil War medicine, as seen in the PBS series, Mercy Street ...
McNish, Megan E., Sutter, Meg A.
core  

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