Results 101 to 110 of about 893,085 (281)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
In 1961, when the Krasinski Palace (the Palace of the Republic) was rebuilt, it was given to the National Library's use. All the departments of the Division of Special Collections were placed in the Palace, including the map department.
Lucyna Szaniawska
doaj +1 more source
Interview with Donald Gallion, August 6, 2008
Donald Gallion was interviewed on August 6, 2008 by Michael Birkner about his time serving in the United States army during WWII and his return to Gettysburg College and after the war. Collection Note: This oral history was selected from the Oral History
Birkner, Michael J., Gallion, Donald
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Interview with Karl Mattson, August 10, 2011
Karl Mattson was interviewed on August 10, 2011 by Michael Birkner about his life starting with his earliest memories. This interview is part 1 of a 2 part interview.
Birkner, Michael J., Mattson, Karl
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
It’s the Collections that are Special
In the Library with the Lead Pipe is pleased to welcome another guest author, Lisa Carter! Lisa has just recently been appointed as Visiting Program Officer to work with the Association of Research Libraries Special Collections Working Group.
Lisa Carter
doaj
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

