Results 121 to 130 of about 11,363,089 (416)

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Sociolinguistic conotation of the term “chimerical groups” in school

open access: yesSpecialusis Ugdymas, 2017
Chimerical groups at school are a new pedagogical reality observed in the behavior of communities prone to deviant activities. The different interpretations link these communities to difficult children, youth subcultures, and street gangs while ...
Nikolay Tsankov, Veska Guyviiska
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Social and professional skills of adolescents with autism spectrum disorders

open access: yesSpecialusis Ugdymas, 2018
The article deals with investigation of professional skills of adolescents with autism spectrum disorders (ASD). 40 ukrainian adolescents of 13-17 years old were investigated by use of Psychological and Educational Profile for Youth and Adult (AAPEP ...
Kateryna Ostrovska   +2 more
doaj   +1 more source

Introduction to special section on Māori culture and education. [PDF]

open access: yes, 2002
An introduction is presented in which the editor discusses various reports within the issue on topics including the need for coordinated language policy, the Treaty of Waitangi, and ...
Bishop, Russell
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Enhancing social skills of children with autism spectrum disorder: The impact of differentiated learning in inclusive elementary schools

open access: yesJournal of Educational Management and Instruction
This study investigates the implementation of the differentiated learning model as a strategy to enhance social skills in children with autism spectrum disorder (ASD). Adopting a qualitative approach with a descriptive method, data were gathered through
Ana Lisdiana   +3 more
doaj   +1 more source

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