Results 41 to 50 of about 12,064,789 (291)

The Application of “Internet+” in the Ageing Adaptation of Elderly People with Disabilities at Home

open access: yesJournal of Mathematics, 2021
This paper focuses on the role of the Internet in empowering social work to intervene in ageing-in-place services for the disabled elderly in terms of time, space, and resources.
Huang Juan   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

A Typical report: Newsletter of the Special Education Section [Vol. 7, No. 1]

open access: yes, 1973
"October, 1973.""A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel.
Kansas. Special Education Administration Section.
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Other title: Part B annual performance report

open access: yes, 2004
Annual; Began with Reporting period July 1, 2002/June 30, 2003.; Submitted to the U.S. Office of Special Education Programs (OSEP).; Volumes for reporting period July 1, 2002/June 30, 2003- also called ...
Connecticut. Bureau of Special Education.
core   +5 more sources

A proposed program to benefit from the combination of wood veneer inlays and embroidered wood to train the deaf and hard of hearing to establish a micro-productive project

open access: yesJournal of Architecture, Art & Humanistic Science
The current research aims at a proposed program to take advantage of the combination of wood veneer inlays and embroidered wood to train the deaf and hard of hearing to establish a micro-productive project at Al-Amal School for the Deaf and Hard of ...
DR. Samar Rizk Mohamed Nassem Lecturer of Wood Working Special Breeding – Art Education Department Faculty of Special Education - Faculty of Education, Damietta University
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A Typical report: Newsletter of the Special Education Section [Vol. 6, No. 2]

open access: yes, 1973
"February, 1973.""A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel. It is anticipated that this newsletter
Kansas. Special Education Administration Section.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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