Results 51 to 60 of about 983,776 (314)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The impact of appearance anxiety on loneliness among college students: an integrative model

BMC Psychology
Background The widespread use of social media has made appearance anxiety increasingly prevalent among college students and has been linked with mental health concerns.
Jianbao Chang, Dehua Guo, Shiqin Dai
doaj   +1 more source

Development of an early intervention guidebook for students with physical disabilities as special education students learning support

Research and Development in Education
Students with physical disabilities often face barriers in accessing appropriate early intervention resources within special education settings. This study focuses on addressing the lack of structured and accessible guidebooks designed specifically to ...
Endang Pudjiastuti Sartinah, S. Sujarwanto, Diah Anggraeny, Endang Purbaningrum, Faizur Rahmatin   +4 more
doaj   +1 more source

Strategy Use on Bounded and Unbounded Number Lines in Typically Developing Adults and Adults With Dyscalculia: An Eye-Tracking Study

Journal of Numerical Cognition, 2018
Recent research suggests that bounded number line tasks, often used to measure number sense, measure proportion estimation instead of pure number estimation. The latter is thought to be measured in recently developed unbounded number line tasks. Children
Fae Aimée van der Weijden, Erica Kamphorst, Robin Hella Willemsen, Evelyn H. Kroesbergen, Anne H. van Hoogmoed   +4 more
doaj   +1 more source

A Typical report: Newsletter of the Special Education Section [Vol. 5, No. 3]

, 1971
"May, 1971." Issue mis-labeled as Vol. 4, no. 3."A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel.
Kansas. Special Education Administration Section.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Special Education Instructional Paraprofessional in Kansas

, 1970
"This project is funded by a grant through the United States Office of Education, Special Education Program, Grant G008530019."--Page [7 of 8].Who is a Special Education Instructional Paraprofessional? What is the History of the Paraprofessional?
Kansas. Special Education Paraprofessional Community College Program.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Gender aspects in victim behavior among adolescents

Specialusis Ugdymas, 2016
Research has been necessitated by the current situation in our society where the victim behavior is forming among children and adolescents and their gender roles are changing.
Roza A. Valeeva, Natalia N. Litvinova, Ewa M. Kulesza   +2 more
doaj   +1 more source

A Typical report: Newsletter of the Special Education Section [Vol. 7, No. 1]

, 1973
"October, 1973.""A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel.
Kansas. Special Education Administration Section.
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