Results 71 to 80 of about 12,064,789 (291)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
A Typical report: Newsletter of the Division of Special Education [Vol. 4, No. 1]
"October 1970.""A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local districts as follows: Provide a means of communication for special education ...
Kansas. State Department of Education. Division of Special Education.
core +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
A Typical report: Newsletter of the Special Education Section [Vol. 6, No. 1]
"November 1972." Issue mis-labeled as Vol. 5, No. 1."A report to cover all areas of special education and to serve as a clearing house through which pertinent information is disseminated to local school administrators and special education personnel.
Kansas. Special Education Administration Section.
core +1 more source
Knowledge of people with visual impairment about contraceptives: an exploratory study
Background Knowledge and information about contraceptives are key factors for the protection of reproductive health. Evidence from various parts of the world reveal that women with disabilities are facing widespread barriers in accessing public services.
Dunja Stekić Djindjić +4 more
doaj +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Xinyu Wei, Qian Du, Dehui Ma, Xiaobo Guo, Qianxiang YangCollege of Special Education, Changchun University, Changchun, Jilin, 130022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Dehui Ma, College of ...
Wei X, Du Q, Ma D, Guo X, Yang Q
doaj
Purpose of the study. Identification and clarification of the dynamics of cognitive and personality educational achievements of primary school students with autistic spectrum disorders and intellectual disorders in the learning process in ...
M.M. Libling +3 more
doaj +1 more source

