Results 71 to 80 of about 4,266,161 (351)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The development and validation of the intercultural communicative competence evaluation instrument (ICCEI)

Cogent Education
English foreign language (EFL) teachers’ intercultural communicative competence (ICC) is crucial for effective culturally responsive language learning and learners’ development of ICC.
K. Tsatzali, E. Beazidou, G. Stavropoulou, K. Botsoglou, G. Andreou   +4 more
doaj   +1 more source

From library skills to information literacy [PDF]

, 2005
The application of new technologies and the acquisition of new sources and methods of information dissemination, as well as the provision of libraries services, requires the special education of the users in order to take advantage of these sources and ...
Nikitakis, Michail, Papadourakis, George, Sitas, Anestis   +2 more
core  

Introduction to special edition. [PDF]

, 2010
This special issue of the Waikato Journal of Education arose from a symposium held at The University of Waikato in June, 2009. The symposium, Initial Teacher Education and the New Zealand Curriculum–Te Marautanga o Aotearoa Symposium, was attended by ...
Cooper, Beverley, McGee, Clive
core   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Exploring indicators of natural recovery from alcohol and drug use problems: findings from the life in recovery survey in Flanders

Substance Abuse Treatment, Prevention, and Policy
Introduction Research has established natural recovery (NR) as an important pathway to substance use recovery. Studies investigating correlates of NR have mainly focused on demographic and substance use variables rather than life circumstances.
Florian De Meyer, Amine Zerrouk, Clara De Ruysscher, Wouter Vanderplasschen   +3 more
doaj   +1 more source

Development of an early intervention guidebook for students with physical disabilities as special education students learning support

Research and Development in Education
Students with physical disabilities often face barriers in accessing appropriate early intervention resources within special education settings. This study focuses on addressing the lack of structured and accessible guidebooks designed specifically to ...
Endang Pudjiastuti Sartinah, S. Sujarwanto, Diah Anggraeny, Endang Purbaningrum, Faizur Rahmatin   +4 more
doaj   +1 more source

Strategy Use on Bounded and Unbounded Number Lines in Typically Developing Adults and Adults With Dyscalculia: An Eye-Tracking Study

Journal of Numerical Cognition, 2018
Recent research suggests that bounded number line tasks, often used to measure number sense, measure proportion estimation instead of pure number estimation. The latter is thought to be measured in recently developed unbounded number line tasks. Children
Fae Aimée van der Weijden, Erica Kamphorst, Robin Hella Willemsen, Evelyn H. Kroesbergen, Anne H. van Hoogmoed   +4 more
doaj   +1 more source

Editorial: BILETA special issue: Technology and Legal Education [PDF]

, 2014
Fragmentation and convergence are two discoursal lenses that have been used to view changes that have taken place in the domains of legal services,the legal profession, regulation and legal education. While they may appear orthogon al, the relationships
Maharg, P
core   +3 more sources

Autism: A Function of Neurodiversity? [PDF]

, 2020
In a culture filled with changes and challenges, there is a need to support groups of people with differences. Neurodiversity is a concept where neurological differences are to be recognized and respected as any other human variation.
Murdock, Jan
core   +1 more source