Results 71 to 80 of about 8,032,770 (318)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Validity of two general outcome measures of science and social studies achievement

open access: yesSpecialusis Ugdymas, 2016
The present research expanded validity findings for a structured formative assessment measure of content learning that was administered online and known as critical content monitoring.
Paul Mooney   +3 more
doaj   +1 more source

The Benefits and Challenges of Special Education Positions in Rural Settings: Listening to the Teachers

open access: yesRural Education, 2018
Special education teachers, through a national survey conducted in 55 rural districts, provided information on the positive and negative aspects of teaching in rural schools.
A. Berry, M. Gravelle
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Assessment of the efficiency of the integrated application of educational software when teaching children with mild intellectual disabilities (MID)

open access: yesSpecialusis Ugdymas, 2017
Learning software for children with intellectual disabilities is particularly important because some of the solutions are highly practical, allowing for easy presentation of different types of incentives and goals, often with higher quality than other ...
Efstratios Pantelis, Nikolay Tsankov
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Teacher education for inclusion - the premises for implementing a new initial teacher training programme

open access: yesSpecialusis Ugdymas, 2016
This paper attempts to highlight and examine the Romanian perspective regarding inclusive education by presenting some statistical data and the steps that have been made in order to make the switch from a school system lead by the segregation principle ...
Elena Marin
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

An exploratory study of children’s expressive language productivity in relation to teachers’ use of communication-supporting strategies

open access: yesFrontiers in Education
Supporting children’s language development, particularly oral language, is crucial as it constitutes the basis for the further development of literacy skills. This study explored patterns of primary school children’s expressive language productivity over
Karin Edlund   +3 more
doaj   +1 more source

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