Results 71 to 80 of about 11,214,713 (348)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The development and validation of the intercultural communicative competence evaluation instrument (ICCEI)

Cogent Education
English foreign language (EFL) teachers’ intercultural communicative competence (ICC) is crucial for effective culturally responsive language learning and learners’ development of ICC.
K. Tsatzali, E. Beazidou, G. Stavropoulou, K. Botsoglou, G. Andreou   +4 more
doaj   +1 more source

Nutritional needs of children with disabilities in the UAE: understanding predictors and mediators of nutritional knowledge and practices

BMC Nutrition, 2022
Background There is a high estimated prevalence of obesity and poor eating habits among children with disabilities. Unfortunately, the extent of parental and teachers’ awareness of the dietary needs and nutritional requirements of children with ...
Maxwell Peprah Opoku, Ashraf Moustafa, Noora Anwahi, Hala Elhoweris, Fatima Alkatheeri, Najwa Alhosani, Anwar Alameri, Shashidhar Belbase   +7 more
doaj   +1 more source

Meta analysis for special education leadership in Malaysia [PDF]

, 2020
The leadership of the headmaster as the school's chief administrator is crucial in determining the school's direction of success. Practiced leadership also reflects school culture and teachers' performance. This will help to ensure the success of the
Abdul Razzaq, Abdul Rasid, Ahad, Rosnee, Mosbiran, Nor Fauziyana, Mustafa, Mohamad Zaid, Nordin, Mohd Norazmi   +4 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Development of an early intervention guidebook for students with physical disabilities as special education students learning support

Research and Development in Education
Students with physical disabilities often face barriers in accessing appropriate early intervention resources within special education settings. This study focuses on addressing the lack of structured and accessible guidebooks designed specifically to ...
Endang Pudjiastuti Sartinah, S. Sujarwanto, Diah Anggraeny, Endang Purbaningrum, Faizur Rahmatin   +4 more
doaj   +1 more source

Features of School Adaptation of Pupils with Autism Spectrum Disorder in the First Year of Study

Клиническая и специальная психология, 2023
The article discusses the results of the initial stage of a longitudinal study of the school adaptation of children with autism spectrum disorders studying in primary school.
I.D. Antonova, I.A. Kostin
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Development of the Fog Seal Layer Characterized by Durability in Terms of Skid Resistance

Advances in Materials Science and Engineering, 2021
In this paper, based on the thermosetting properties, bonding performance, high-temperature water damage resistance, and aging resistance properties of epoxy-emulsified asphalt, the best formulation of epoxy emulsified asphalt as a skid resistance fog ...
Yingjun Jiang, Jiangtao Fan, Pengyu Lv, Kejia Yuan, Yong Yi, Tian Tian, Chenfan Bai   +6 more
doaj   +1 more source

Features of Personal Distress of Teachers of Special and Inclusive Education

Клиническая и специальная психология, 2023
The article presents the results of a study of personal distress and its relationship with indicators of psychological well-being and professional burnout among teachers with different experience of working with students with learning ...
A.M. Fedoseeva, N.V. Babkina
doaj   +1 more source