Results 71 to 80 of about 421,880 (306)

Perspectives of professionals on the perinatal period as a window of opportunity for change in women with SUD: insights from healthcare, child welfare, substance use, and child protection services

Frontiers in Psychiatry
IntroductionThe perinatal period is widely recognized as a time of profound transition and heightened vulnerability, particularly for women with substance use disorders (SUD). Adopting a strengths-based perspective, this qualitative study aims to explore
Sarah Vandewalle, Sara Rowaert, Gilbert Lemmens, Gilbert Lemmens, Sarah De Pauw, Wouter Vanderplasschen   +5 more
doaj   +1 more source

The Effectiveness of Dweck’s Mind Set Intervention on Students’ Negative Orientation Towards Problem and Hopelessness during the COVID-19 [PDF]

پژوهش‌های کاربردی روانشناختی
Aim: The aim of the present study was to investigate the Effectiveness of Dweck’s Mindset intervention on negative orientation towards problem and hopelessness in high school students.
Bahar Rashidi, Ahmad Abedi, Salar Faramarzi   +2 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Working from a distance? A study of Special Educational Needs Coordinators in Swedish preschools

, 2020
Working from a distance?
Petra Gäreskog, Gunilla Lindqvist
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Social-Emotional Learning (SEL) and Its Impact on Teacher Stress, Self-Efficacy, and Attitudes Towards Inclusion: Longitudinal Insights from the StaFF-BL Project

Behavioral Sciences
Social-emotional and behavioural difficulties are among the most common developmental problems in childhood and adolescence and present substantial challenges for teachers and schools.
Dennis Christian Hövel, Patrizia Röösli, Ankica Jurkic, Melanie Nideröst, Pierre-Carl Link, Fabio Sticca   +5 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Diversified transitions and educational equality? Negotiating the transitions of young people with immigrant backgrounds and/or special educational needs

, 2020
The focus of this contribution is on the targeted transition practices of career guidance and on the opportunity structures they frame for young people with immigrant backgrounds and/or special educational needs.
Mira Kalalahti, Annukka Niemi, Janne Varjo, Markku Jahnukainen   +3 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Treatment outcomes for substance use disorders across the African continent: a systematic review

BMC Psychology
Background Substance use disorders (SUDs) are increasingly recognized as a significant public health concern in Africa, placing considerable strain on the economy, healthcare system, and society at large.
Claire Biribawa, Nazarius Mbona Tumwesigye, Deborah Louise Sinclair, Duncan Kabiito Matovu, Greg Swensen, Florian De Meyer, Moses Mukasa, David Kalema, Byamah Brian Mutamba, Wouter Vanderplasschen   +9 more
doaj   +1 more source