Results 61 to 70 of about 628,817 (310)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Effectiveness of a culturally adapted online video module for enhancing parental hearing aid management skills in a quasi-experimental study

Scientific Reports
Parents play a crucial role in supporting children with hearing aids (HA), yet they often lack access to comprehensive information on HA care and management.
Rafidah Mazlan, Alicia Gek Ching Tan, Wan Nur Hanim Mohd Yusoff, Nur ‘Izzati Md Yusoff, Mohamad Firdaus Latip, Jamilah Kadir, Mohd Azlis Sani Md Jalil, Mohd Zulkarnain Abdul Wahab, Mohd Anis Abdul Razak, Hanani Harun Rasit   +9 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Dr. Diyana creates Hear Me app to assist students with special needs [PDF]

, 2021
KUANTAN, 5 July 2021 - For more than a year, the country has been facing the Covid-19 pandemic. Since then, a new norm learning environment has been established to implement home-based teaching and learning (PdPR) for students, including those with ...
Nor Salwana, Mohammad Idris
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

History of Education and Care of Children with Special Needs : Terakoya era to Now

, 2005
In Japan young children with special needs have been integrated in day nurseries since around 1970. In general, Japanese educational system has segregated non handicapped children with handicapped children since The Meiji Era.
Sato, Yoko, 佐藤, 陽子, サトウ, ヨウコ   +2 more
core   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Minutes of Meeting: Library Services to People with Special Needs Section (Teleconference, Zoom), 25 October, 2022

, 2023
Minutes of business meeting of Library Services to People with Special Needs Section held via Zoom on 25 October ...
IFLA Library Services to People with Special Needs Section Standing Committee
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source