Results 61 to 70 of about 114,803 (249)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Special Holonomy on Special Spaces
, 2014 We characterise simply-connected biquotients which potentially admit metrics of holonomy G_2. We prove that there are at most three real homotopy types of rationally elliptic such manifolds---all of them being formal. In the course of this examination we classify rationally elliptic homotopy types and characterise 7-dimensional simply-connected ...
openaire +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Sudan Journal of Medical Sciences, 2019 Background: Hepatocellular carcinoma (HCC) represents a fifth of common malignancies, with an annual diagnosis of 750,000 new cases. It is the third cause of cancer deaths worldwide.
Wael Mohialddin Ahmed Doush +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Discover Public HealthBackground Ergonomics is the design of efficiency and comfort in the working environment. Neglecting surgical ergonomics might lead to early retirement and decreased productivity.
Imtinan Yousif +2 more
doaj +1 more source
Journal of Cardiovascular Development and DiseaseTranscatheter Aortic Valve Implantation (TAVI) is an effective treatment for severe aortic stenosis in high-risk patients; however, atrial fibrillation (AF) is a common complication associated with the procedure.
John Fernando Montenegro-Palacios +5 more
doaj +1 more source