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Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan+9 more
wiley +1 more source
The Organization of Production and Economic Development [PDF]
A formalization of the Coase-Williamson-Cheung theory of the firm is used to examine the trade-off between the firm and the market as institutions for organizing production in a dynamic, general equilibrium model with increasing returns to labor ...
Lewis S. Davis
core
Sport Specialization by Youth Athletes [PDF]
Sport specialization and sampling are two ways youth athletes can play sports. Athletes playing in college, at the Division III level, sample sports throughout their childhood instead of specializing in one sport.
Campbell, Ian
core +1 more source
Background Ergonomics is the design of efficiency and comfort in the working environment. Neglecting surgical ergonomics might lead to early retirement and decreased productivity.
Imtinan Yousif+2 more
doaj +1 more source
Background: Hepatocellular carcinoma (HCC) represents a fifth of common malignancies, with an annual diagnosis of 750,000 new cases. It is the third cause of cancer deaths worldwide.
Wael Mohialddin Ahmed Doush+1 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts+8 more
wiley +1 more source
Specialization in the Presence of Trade and Financial Integration: Explorations of the Integration-Specialization Nexus [PDF]
In this paper we investigate the economic integration - industrial specialization nexus and unravel the relationship between trade and financial openness and industrial specialization.
Bos Jaap W.B.+2 more
core +1 more source
Disturbance and Clonal Reproduction Determine Liana Distribution and Maintain Liana Diversity in a Tropical Forest [PDF]
Negative density dependence (NDD) and habitat specialization have received strong empirical support as mechanisms that explain tree species diversity maintenance and distribution in tropical forests.
Ledo, Alicia, Schnitzer, Stefan A.
core +1 more source