Results 51 to 60 of about 2,949,493 (224)

Treatment With a Marine Oil Supplement Alters Lipid Mediators and Leukocyte Phenotype in Healthy Patients and Those With Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Peripheral artery disease (PAD) is an advanced form of atherosclerosis characterized by chronic inflammation. Resolution of inflammation is a highly coordinated process driven by specialized pro‐resolving lipid mediators endogenously derived ...
Melinda S. Schaller, Mian Chen, Romain A. Colas, Thomas A. Sorrentino, Ann A. Lazar, S. Marlene Grenon, Jesmond Dalli, Michael S. Conte   +7 more
doaj   +1 more source

Specialized Pro-resolving Mediators: Resolving Inflammation and Restoring Bone [PDF]

, 2023
Periodontitis is a chronic inflammatory disease characterized by gingival inflammation and loss of periodontal ligament attachment, which if severe enough can lead to the irreversible destruction of surrounding alveolar bone.
Tran, Amber, Raglin, Amber, Bilbrey, Carrie Nichole   +2 more
core   +1 more source

Prostanoids and Resolution of Inflammation – Beyond the Lipid-Mediator Class Switch

Frontiers in Immunology, 2021
Bioactive lipid mediators play a major role in regulating inflammatory processes. Herein, early pro-inflammatory phases are characterized and regulated by prostanoids and leukotrienes, whereas specialized pro-resolving mediators (SPM), including lipoxins,
Tobias Schmid, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne   +4 more
doaj   +1 more source

Current knowledge of the implication of lipid mediators in psoriasis

Frontiers in Immunology, 2022
The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard, Mélissa Simard, Sophie Morin, Sophie Morin, Zainab Ridha, Roxane Pouliot, Roxane Pouliot   +6 more
doaj   +1 more source

EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study.

Atherosclerosis, 2020
BACKGROUND AND AIMS The independent effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on chronic inflammation through their downstream lipid mediators, including the specialized pro-resolving lipid mediators (SPM), remain unstudied ...
Jisun So, Da-Yong Wu, A. Lichtenstein, A. Tai, N. Matthan, K. Maddipati, S. Lamon-Fava   +6 more
semanticscholar   +1 more source

In vivo availability of pro-resolving lipid mediators in oxazolone induced dermal inflammation in the mouse [PDF]

, 2015
The activation and infiltration of polymorphonuclear neutrophils (PMN) are critical key steps in inflammation. PMN-mediated inflammation is limited by anti-inflammatory and pro-resolving mechanisms, including specialized pro-resolving lipid mediators ...
Geisslinger, Gerd, Gerd Geisslinger, Scholich, Klaus, Bruin, Natasja de, Klaus Scholich, Ferreirós Bouzas, Nerea, Natasja de Bruin (829628), Gerd Geisslinger (109814), Mike Schmidt, Julia Homann, Jing Suo, Julia Homann (829627), Suo, Jing, Mike Schmidt (255975), Klaus Scholich (494697), Natasja de Bruin, Nerea Ferreirós, Schmidt, Mike, Homann, Julia, Jing Suo (494693), Nerea Ferreirós (440014)   +20 more
core   +2 more sources

The Natural Combination Medicine Traumeel (Tr14) Improves Resolution of Inflammation by Promoting the Biosynthesis of Specialized Pro-Resolving Mediators

Pharmaceuticals, 2021
The resolution of inflammation is an integral part of the acute inflammatory response and eventually leads to the return to homeostasis. It is supported by specialized pro-resolving mediators (SPMs) that act as immunoresolvents via specific G-protein ...
Paul M. Jordan, Emeline van Goethem, Andrea M. Müller, Kathrin Hemmer, Virginie Gavioli, Vincent Baillif, Yvonne Burmeister, Natascha Krömmelbein, Marc Dubourdeau, Bernd Seilheimer, Oliver Werz   +10 more
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Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

Frontiers in Pharmacology, 2022
Introduction: Sex differences in inflammation are obvious and contribute to divergences in the incidence and severity of inflammation-related diseases that frequently preponderate in women. Lipid mediators (LMs), mainly produced by lipoxygenase (LOX) and
Fabiana Troisi, Simona Pace, Paul M. Jordan, Katharina P. L. Meyer, Rossella Bilancia, Armando Ialenti, Francesca Borrelli, Antonietta Rossi, Lidia Sautebin, Charles N. Serhan, Oliver Werz   +10 more
doaj   +1 more source

Cyclopentenone-containing oxidized phospholipids and their isoprostanes as pro-resolving mediators of inflammation. [PDF]

, 2017
Inflammation represents a powerful innate immune response that defends tissue homeostasis. However, the appropriate termination of inflammatory processes is essential to prevent the development of chronic inflammatory disorders.
Friedli, Olivier, Olivier Friedli, Freigang, Stefan Bernd, Stefan Freigang   +3 more
core   +1 more source

Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201

Journal of Inflammation Research, 2022
Christian Kretzer,1 Paul M Jordan,1 Rossella Bilancia,2 Antonietta Rossi,2 Tuğçe Gür Maz,3 Erden Banoglu,3 Ulrich S Schubert,4,5 Oliver Werz1,5 1Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University
Kretzer C, Jordan PM, Bilancia R, Rossi A, Gür Maz T, Banoglu E, Schubert US, Werz O   +7 more
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