Results 51 to 60 of about 7,659,035 (307)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Effects of Different Levels of Starch and Cellulose Diets on the Growth and Physiological and Biochemical Indicators of Cyprinus carpio

open access: yesGuangdong nongye kexue
【Objective】This research aimed to investigate the impacts of diets with different ratios of starch to cellulose on the growth, and physiological and biochemical indices of common carp (Cyprinus carpio). The findings were intended to provide a theoretical
Zhixin ZHANG   +8 more
doaj   +1 more source

Investigating Co-occurrence among Look-alike Species: The Case of Three Bears in Northeast India

open access: yesDiversity, 2022
At the most basic level, the assessment of a species’ status involves knowing where it occurs. Determining the presence of rare species is difficult, and can be further confounded by the presence of a more common look-alike species.
David L. Garshelis   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Applying the Key Biodiversity Area Standard to Important Sites for Sharks

open access: yesConservation Letters
The Kunming‐Montreal Global Biodiversity Framework commits nations to conserving 30% of coastal and marine areas, “especially areas of particular importance for biodiversity.” Key Biodiversity Areas (KBAs) provide a standardized approach for recognizing ...
Charlotte Boyd   +7 more
doaj   +1 more source

Invasive Species and Climate Change [PDF]

open access: yes, 2010
ISSUE Climate change interacts with and can often amplify the negative impacts of invasive species. These interactions are not fully appreciated or understood.
Invasive Species Advisory Committee
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A chromosome-level reference genome assembly of the giant pangasius (Pangasius sanitwongsei)

open access: yesScientific Data
The giant pangasius (Pangasius sanitwongsei) is a critically endangered freshwater species with considerable ecological and economic significance in Southeast Asia and southern China.
Baojiang Gan   +9 more
doaj   +1 more source

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