Results 51 to 60 of about 7,659,035 (307)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
【Objective】This research aimed to investigate the impacts of diets with different ratios of starch to cellulose on the growth, and physiological and biochemical indices of common carp (Cyprinus carpio). The findings were intended to provide a theoretical
Zhixin ZHANG +8 more
doaj +1 more source
Investigating Co-occurrence among Look-alike Species: The Case of Three Bears in Northeast India
At the most basic level, the assessment of a species’ status involves knowing where it occurs. Determining the presence of rare species is difficult, and can be further confounded by the presence of a more common look-alike species.
David L. Garshelis +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Applying the Key Biodiversity Area Standard to Important Sites for Sharks
The Kunming‐Montreal Global Biodiversity Framework commits nations to conserving 30% of coastal and marine areas, “especially areas of particular importance for biodiversity.” Key Biodiversity Areas (KBAs) provide a standardized approach for recognizing ...
Charlotte Boyd +7 more
doaj +1 more source
Invasive Species and Climate Change [PDF]
ISSUE Climate change interacts with and can often amplify the negative impacts of invasive species. These interactions are not fully appreciated or understood.
Invasive Species Advisory Committee
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A chromosome-level reference genome assembly of the giant pangasius (Pangasius sanitwongsei)
The giant pangasius (Pangasius sanitwongsei) is a critically endangered freshwater species with considerable ecological and economic significance in Southeast Asia and southern China.
Baojiang Gan +9 more
doaj +1 more source

