Results 61 to 70 of about 10,139,462 (316)
Knotszakpijp - Styela clava. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]
Oorspronkelijk leefde de knotszakpijp Styela clava enkel langs Aziatische kusten. Transport via vasthechting op oorlogsschepen bracht de soort naar Europa, waar hij voor het eerst opgemerkt werd in Engeland omstreeks 1953.
VLIZ Alien Species Consortium
core
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Penseelkrab - Hemigrapsus takanoi. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]
De penseelkrab Hemigrapsus takanoi kwam oorspronkelijk enkel voor in de Noordwest-Pacifische regio, maar werd via transportschepen - als larven in het ballastwater of in de aangroeilaag op de romp - naar Europa gebracht.
VLIZ Alien Species Consortium
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
A new specialist group for Brazilian fungi
Elisandro Ricardo Drechsler-Santos +10 more
doaj +1 more source
Genome skimming herbarium specimens for DNA barcoding and phylogenomics
Background The world’s herbaria contain millions of specimens, collected and named by thousands of researchers, over hundreds of years. However, this treasure has remained largely inaccessible to genetic studies, because of both generally limited success
Chun-Xia Zeng +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Zuiders waterezeltje - Proasellus coxalis. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]
Het zuiders waterezeltje Proasellus coxalis is een zoetwaterpissebed, die oorspronkelijk enkel voorkwam in rivieren en riviermondingen rond het Middellandse Zeegebied.
VLIZ Alien Species Consortium
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

