Results 61 to 70 of about 7,659,035 (307)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Characteristic of complete mitochondrial genome and phylogenetic status of a muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in South Korea

open access: yesMitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of Muskrat, Ondatra zibethicus (Rodentia: Cricetidae) in Korea was sequenced for the first time using the next-generation sequencing method to understand its evolutionary relationship and to be helpful to establish a ...
Young-Chae Kim   +7 more
doaj   +1 more source

Development of InDel markers for interspecific hybridization between hill pigeons and feral pigeons based on whole-genome re-sequencing

open access: yesScientific Reports, 2022
Interspecific hybridization occurs among birds, and closely related sister taxa tend to hybridize at a high rate. Genomic hybridization markers are useful for understanding the patterns and processes of hybridization and for conserving endangered species
Jin-Yong Kim   +9 more
doaj   +1 more source

Invasive Species Impacts on Infrastructure [PDF]

open access: yes, 2016
Executive Summary Invasive species represent one of the most significant threats to ecosystems, human and animal health, infrastructure, the economy, and cultural resources.
Invasive Species Advisory Committee
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Biofuels: Cultivating Energy, not Invasive Species [PDF]

open access: yes, 2009
Biofuels: Cultivating Energy, not Invasive Species, approved by ISAC on August 11, 2009 ISSUE To provide alternatives to petroleum-based energy, the United States government has mandated a greater proportion of plant-based biofuels be integrated into its
Invasive Species Advisory Committee
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

ON SPECIES OF CATOCALA [PDF]

open access: yesThe Canadian Entomologist, 1876
The male is now taken by Mr. Jas. Angus. The species is larger than obscura,agreeing with it in tone and in the white fringes of hind wings; it may be distinguished by the strongly marked median lines of primaries with a deeper toothing. The lines in obscura are thread-1ike, inconspicuous, and with shallower indentations.
openaire   +2 more sources

Invasive Species Definition Clarification and Guidance White Paper

open access: yes, 2006
Paper discussing a "a non-regulatory policy interpretation of the term invasive species" through a positional defintion of what and what does not constittue an invasive species along with examples of impacts caused by invasive species.
Definitions Subcommittee of the Invasive Species Adivsory Committee
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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