Results 71 to 80 of about 8,964,438 (367)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

The chromosome-level genome assembly and genes involved in biosynthesis of nervonic acid of Malania oleifera

open access: yesScientific Data, 2023
Nervonic acid (C24:1 Δ15, NA) is a very long-chain monounsaturated fatty acid, a clinically indispensable resource in maintaining the brain and nerve cells development and regeneration.
Tianquan Yang   +10 more
doaj   +1 more source

Species highs [PDF]

open access: yesCurrent Biology, 2009
SummaryA new report highlights the threat of climate change to new species discovered in the eastern Himalayas over recent years, writes Nigel Williams.
openaire   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

A heuristic view about the evolution and species [PDF]

open access: yesarXiv, 2010
The controversy concerning both the definition of the species and methods for inferring the boundaries and numbers of species has occupied biologists for centuries, and the debate itself has become known as the species problem. The modern theory of evolution depends on a fundamental redefinition of "species".
arxiv  

Building a Corpus for Biomedical Relation Extraction of Species Mentions [PDF]

open access: yesarXiv, 2023
We present a manually annotated corpus, Species-Species Interaction, for extracting meaningful binary relations between species, in biomedical texts, at sentence level, with a focus on the gut microbiota. The corpus leverages PubTator to annotate species in full-text articles after evaluating different Named Entity Recognition species taggers.
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Sorption and Environmental Risks of Phosphorus in Subtropical Forest Soils

open access: yesAdsorption Science & Technology, 2021
Phosphorus (P) is one of the key limiting factors for the growth of forests and their net primary productivity in subtropical forest ecosystems. Phosphorus leaching of the forest soil to the catchment and groundwater in karst region is the main source of
Jianhong Liang   +4 more
doaj   +1 more source

Identifying the Rooted Species Tree from the Distribution of Unrooted Gene Trees under the Coalescent [PDF]

open access: yesarXiv, 2009
Gene trees are evolutionary trees representing the ancestry of genes sampled from multiple populations. Species trees represent populations of individuals -- each with many genes -- splitting into new populations or species. The coalescent process, which models ancestry of gene copies within populations, is often used to model the probability ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

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