Results 121 to 130 of about 3,722,802 (358)

Evolutionary and geographical history of the Leishmania donovani complex with a revision of current taxonomy.

, 2007
Leishmaniasis is a geographically widespread severe disease, with an increasing incidence of two million cases per year and 350 million people from 88 countries at risk. The causative agents are species of Leishmania, a protozoan flagellate.
Ayala, Francisco J, Chocholová, Eva, Dedet, Jean-Pierre, Dujardin, Jean-Claude, Haralambous, Christos, Horák, Ales, Jirků, Milan, Kuhls, Katrin, Lukes, Julius, Mauricio, Isabel L, Miles, Michael A, Oborník, Miroslav, Pratlong, Francine, Schönian, Gabriele, Soteriadou, Ketty, Tintaya, K Wilber Quispe   +15 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A puzzle no more: the identity of Spirobranchus tetraceros (Schmarda, 1861) (Annelida, Serpulidae) is revealed

Records of the Australian Museum, 2022
Spirobranchus tetraceros (Schmarda, 1861) originally briefly described from New South Wales, Australia was later reported as a widely distributed species of Indo-Pacific origin.
Elena Kupriyanova, Beth Flaxman, Ingo Burghardt   +2 more
doaj   +1 more source

Hyla versicolor-chrysoscelis Species Complex of Gray Treefrogs in Arkansas: Histological and Ultrastructural evidence [PDF]

, 1987
We investigated the Hyla versicolor-chrysoscelis species complex (tetraploid and diploid species, respectively) of cryptic gray treefrogs from Arkansas using light and scanning electron microscopy.
Chaffin, Phyllis, Trauth, Stanley E.
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Species complex diversification by host plant use in an herbivorous insect: The source of Puerto Rican cactus mealybug pest and implications for biological control [PDF]

, 2020
Daniel Poveda Mart nez, Mar a Aguirre, Guillermo A. Logarzo, Stephen D. Hight, Serguei V. Triapitsyn, Hilda Diaz Sotero, Marcelo Diniz Vitorino, Esteban Hasson   +7 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Astyanax henseli, a new name for Tetragonopterus aeneus Hensel, 1870 from southern Brazil (Teleostei: Characiformes)

Neotropical Ichthyology
Tetragonopoterus aeneus Hensel (1870) is removed from synonymy with Astyanax fasciatus (Cuvier, 1819), revalidated and redescribed as A. henseli to avoid homonymy. Astyanax henseli differs from A. fasciatus stricto sensu and other Astyanax species by the
Filipe A. G. de Melo, Paulo A. Buckup
doaj   +1 more source

Data_Sheet_1_Draft Genome Sequence of a New Fusarium Isolate Belonging to Fusarium tricinctum Species Complex Collected From Hazelnut in Central Italy.zip

, 2021
Silvia Turco (11484172), Alessandro Grottoli (11843945), Mounira Inas Drais (11843948), Carlo De Spirito (11843951), Luigi Faino (3517730), Massimo Reverberi (125757), Valerio Cristofori (7536347), Angelo Mazzaglia (166038)   +7 more
openalex   +2 more sources