Results 101 to 110 of about 24,438 (293)

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Genes Suggest Ancestral Colour Polymorphisms Are Shared across Morphologically Cryptic Species in Arctic Bumblebees [PDF]

, 2015
email Suzanne orcd idCopyright: © 2015 Williams et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
Huang Jiaxing, Richardson Leif L., Byvaltsev Alexandr M., Berezin Mikhail V., Williams, ST, Cederberg Björn, Williams, PH, Paul H. Williams (178643), Odegaard, F, Williams Paul H., Rasmussen, Claus Nygaard, Leif L Richardson, Claus Rasmussen, Berezin, Mikhail V., Suzanne T Williams, Alexandr M. Byvaltsev (835449), Cederberg, Björn, Ødegaard Frode, Claus Rasmussen (492702), Sheffield, CS, Frode Ødegaard (833273), Suzanne T. Williams (835453), Jiaxing Huang, Williams Suzanne T., Rasmussen Claus, Cederberg, B, Ødegaard, Frode, Jiaxing Huang (178661), Williams, Suzanne T., Richardson, LL, Richardson, Leif L., Paul H Williams, Frode Ødegaard, Mikhail V Berezin, Berezin, MV, Williams, Paul H., Byvaltsev, Alexandr M., Byvaltsev, AM, Sheffield, Cory S., Leif L. Richardson (835451), Björn Cederberg, Cory S Sheffield, Mikhail V. Berezin (835450), Cory S. Sheffield (835452), Huang, J, Sheffield Cory S., Björn Cederberg (188962), Alexandr M Byvaltsev, Huang, Jiaxing, Rasmussen, C   +49 more
core   +1 more source

Assessing species boundaries using multilocus species delimitation in a morphologically conserved group of neotropical freshwater fishes, the Poecilia sphenops species complex (Poeciliidae).

PLoS ONE, 2015
Accurately delimiting species is fundamentally important for understanding species diversity and distributions and devising effective strategies to conserve biodiversity.
Justin C Bagley, Fernando Alda, M Florencia Breitman, Eldredge Bermingham, Eric P van den Berghe, Jerald B Johnson   +5 more
doaj   +1 more source

ECM‐Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling

Advanced Science, EarlyView.
Prolonged exposure to stiff extracellular matrix drives cancer‐associated fibroblasts into a persistently activated myofibroblast state. Two parallel pathways are identified: β1 integrin activation smoothens the nuclear lamina to reduce lamin–chromatin contacts, while the formin mDia2 regulates nuclear actin to alter chromatin organization.
Swathi Packirisamy, Oscar André, Zhimeng Fan, Pontus Nordenfelt, Vinay S Swaminathan   +4 more
wiley   +1 more source

Systematics and Species Delimitation of the Clownfish-Hosting Sea Anemones: Are There Really Only 10 Host Species?

, 2019
The relationship between clownfishes and sea anemones is one of the most recognizable examples of symbioses on the planet. There are 30 described species of clownfishes, which have adaptively radiated to live with sea anemones, but only 10 nominal ...
Berumen, Michael L., Reimer, J. D., Bartholomew, A., Titus, B. M., Yanagi, K., Meyer, C., Rodriguez, E.   +6 more
core  

DNA-based species delimitation in algae

, 2014
Given the problems of species delimitation in algae using morphology or sexual compatibility, molecular data are becoming the standard for delimiting species and testing their traditional boundaries.
Zuccarello, Giuseppe C, Olivier De Clerck (186236), Pieter Vanormelingen (221944), Lopez-Bautista, Juan M, De Clerck, Olivier, Giuseppe C. Zuccarello (434010), Frederik Leliaert (186222), Verbruggen, Heroen, Vanormelingen, Pieter, Juan M. López-Bautista (435257), Frederique Steen (572886), Leliaert, Frédérik, Heroen Verbruggen (148046), Steen, Frederique   +13 more
core   +1 more source

DNA barcoding for community ecology--how to tackle a hyperdiverse, mostly undescribed Melanesian fauna. [PDF]

, 2012
Trigonopterus weevils are widely distributed throughout Melanesia and hyperdiverse in New Guinea. They are a dominant feature in natural forests, with narrow altitudinal zonation.
Riedel, Alexander, Balke, Michael, Sagata Katayo, Suriani Surbakti (188485), Suriani Surbakti, Tänzler Rene, Riedel Alexander, Sagata, Katayo, Alexander Riedel, Alexander Riedel (188493), Tänzler, Rene, Katayo Sagata, Surbakti, Suriani, Michael Balke, Surbakti Suriani, Balke Michael, Katayo Sagata (188481), Rene Tänzler, Rene Tänzler (188478), Michael Balke (188490)   +19 more
core   +1 more source

Genomic approaches for species delimitation in threatened species

Australasian Plant Conservation: journal of the Australian Network for Plant Conservation, 2021
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source