Results 91 to 100 of about 1,002,080 (260)

Past legacies and future trajectories: climatic refugia, range shifts, and conservation gaps for the endangered Oglethorpe oak (Quercus oglethorpensis)

Frontiers in Forests and Global Change
IntroductionThe endangered Quercus oglethorpensis is a narrowly distributed tree species endemic to the southeastern United States, persisting in fragmented, poorly drained hardwood forests.
Suresh C. Subedi, Binaya Adhikari, Naja Rover, Shivish Bhandari   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Modelling species distribution at the boundaries of the Earth's climate

Global Ecology and Biogeography
11institutetext: Knowledge-based Systems and Document Processing Research Group Faculty of Computer Science Otto-von-Guericke-University Magdeburg 11email: katrin.krieger@ovgu.de Correlative species distribution models (SDMs) are widely used to project the responses of biodiversity to global changes.
Serafini C., Cosentino F., Amori G., Maiorano L.   +3 more
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Using species distribution modelling to identify potential translocation areas for the western chimpanzee under climate change scenarios in Ghana

Global Ecology and Conservation
The Earth’s climate is undergoing drastic changes leading to significant global biodiversity declines. Conservation translocation offers a potential solution for managing or restoring biodiversity threatened by local extinctions due to climate change and
Eric Adjei Lawer, Christopher Akasere, Esther Love Darkoh, Samuel Kojo Annan-Riverson, Edward Debrah Wiafe, Samuel Kingsley Oppong   +5 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Modelling climate-driven range shifts in the distribution of Lantana camara in Ethiopia

Discover Sustainability
Lantana camara L, an invasive species, threatens biodiversity and agricultural systems globally. Its spread is influenced by human activities and climate change, but the interaction between these factors and its invasion is not well understood.
Yikunoamlak Gebrewahid, Berihu Tesfamariam, Daniel Hagos Berhe, Emiru Birhane, Mehari Girmay, Teklay Abebe, Tesfay Teklehaymanot, Gebru Eyasu, Niguse Hagazi, Nigussie Haregeweyn, Takeshi Abe, Selama G. Yebyo   +11 more
doaj   +1 more source