Results 81 to 90 of about 21,526,586 (293)

Inferring the similarity of species distributions using Species’ Distribution Models

Ecography, 2013
A common problem in ecology is our need to reliably compare information on the distributions of distinct species. Since it is not always possible to directly compare the distributions of two species, numerous papers now seek to compare the predictions of Species’ Distribution Models (SDMs, estimates of the probability that two species are present ...
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Examining and addressing the Wallacean shortfall : species distribution modelling and biodiversity patterns of hawkmoths in the old world [PDF]

, 2013
The geographic distribution of the species is one of the basic units of information in ecology and biogeography, yet for the vast majority of the species in the world is quite unknown. It is a phenomenon called the Wallacean shortfall.
Ballesteros-Meja, L.
core   +1 more source

Predicting suitable habitats of parasitic desert species based on Biomod2 ensemble model: Cynomorium songaricum rupr and its host plants as an example

BMC Plant Biology
Background As a species of considerable medicinal, ecological, and economic significance, the protection of C. songaricum and its host plants is of paramount importance.
Lucun Yang, Huamei Jia, Qing Hua
doaj   +1 more source

Invasion Status, Mechanisms, and Future Distribution Prediction of Solidago canadensis in the Trade Port Region: A Case Study of Ningbo Port, China

Plants
Trade ports are the first places where alien species invade and the source of their spread to other areas. Controlling invasions in these regions can effectively reduce invasion pressure and disrupt the spread pathways of invasive species, thereby ...
Xu Luo, Sixiao Shen, Ke Liao, Saiqiang Li, Qinqin Pan, Jiahao Ma, Weiqiang Li, Xiaodong Yang   +7 more
doaj   +1 more source

Did the climate changes cause the extinction of the Late Pleistocene gomphotheres in South America? [PDF]

Zoologia (Curitiba)
A global wave of megafauna extinctions occurred between 50,000 and 10,000 years ago, impacting numerous large continental mammals that are crucial to ecosystem dynamics.
Evelyn N.S. Cruz, Søren Faurby, Ricardo J. Sawaya   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Novel methods for species distribution mapping including spatial models in complex regions [PDF]

, 2014
Species Distribution Modelling (SDM) plays a key role in a number of biological applications: assessment of temporal trends in distribution, environmental impact assessment and spatial conservation planning.
Scott-Hayward, Lindesay Alexandra Sarah
core   +2 more sources

Amphibians reveal unexpectedly large differences in potential climate change responses among ecologically similar habitat specialists

Ecological Indicators
Climate change is substantially impacting earth’s biodiversity, with a massive number of affected species that are difficult to study comprehensively.
Sky T. Button, Donald J. Brown, Jonah Piovia-Scott   +2 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source