Results 61 to 70 of about 21,526,586 (293)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Assessing the freshwater distribution of yellow eel [PDF]

, 2008
In the global context of the decline in wild species, modeling the distribution of populations is a crucial aspect of ecological management. This can be a major challenge, especially for species, such as the European eel, that have complex life cycles ...
Lasne, Emilien, É. Lasne, P. Laffaille, Laffaille, Pascal, Laffaille P., Lasne É.   +5 more
core   +1 more source

Improving multi-species habitat identification through species weighting assignment using joint species distribution model

Ecological Informatics
Habitat conservation serves as the cornerstone for fishery resource recovery. Traditionally, multi-species habitat predictions are typically generated by stacking individual species' habitat suitability maps using the equal-weighting strategy.
Yunlei Zhang, Jie Yin, Yupeng Ji, Chongliang Zhang, Binduo Xu, Yiping Ren, Ying Xue   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Invasive species control: incorporating demographic data and seed dispersal into a management model for Rhododendron ponticum [PDF]

, 2009
Rhododendron ponticum is a serious invasive alien plant in the British Isles and is of significant conservation and economic concern. Here, we integrate information on both the life-history and spatial dynamics of this species within an individual-based,
Edwards, Colin, Atkinson, Rachel, Travis, Justin M, Park, K.J., Harris, Catriona M, Edwards, C., Harris, Catriona, Travis, J.M.J., Park, Kirsty, Atkinson, R.   +9 more
core   +1 more source

Impacts of Climate Change on Alpha and Beta Diversity Patterns of Cerrado anurans

Ecology and Evolution
Climate change poses a major threat to biodiversity, altering species distributions and reshaping ecological communities. In the Brazilian Cerrado, a highly threatened tropical savanna, future climate projections indicate increased temperatures and ...
Amanda Sabino, Gabriela Alves‐Ferreira, Neander Marcel Heming, Gastón Andrés Fernandez Giné, Daniela Custódio Talora   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Biotic modifiers, environmental modulation and species distribution models

, 2012
The ability of species to modulate environmental conditions and resources has long been of interest. In the past three decades the impacts of these biotic modifiers have been investigated as ‘ecosystem engineers’, ‘niche constructors’, ‘facilitators’ and
Schymanski, Stanislaus, Marion, G., Etienne, Rampal S, Kuhn, I., Linder, Peter H., Schymanski, Stanislaus J., Ohlemuller, Ralf, Schymanski, S., Hickler, Thomas, Singer, Alexander, Schymanski, Stanislaus J, Etienne, Rampal S.; id_orcid, Dyke, James, Etienne, Rampal S., Bykova, Olga, Linder, H., Ohlemueller, Ralf, Hickler, T., Singer, A., Marion, Glenn, Kuehn, Ingolf, Linder, H. Peter, Ohlemuller, R., Kuhn, Ingolf, Etienne, R., Linder, H Peter, Bykova, O., Dyke, J.   +27 more
core   +1 more source