Results 151 to 160 of about 9,610,877 (306)

Expectation Cues and False Percepts Generate Stimulus-Specific Activity in Distinct Layers of the Early Visual Cortex. [PDF]

J Neurosci, 2023
Haarsma J, Deveci N, Corbin N, Callaghan MF, Kok P.   +4 more
europepmc   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Improving fMRI in Parkinson's disease by accounting for brain region-specific activity patterns. [PDF]

Neuroimage Clin, 2023
Torrecuso R, Mueller K, Holiga Š, Sieger T, Vymazal J, Ružička F, Roth J, Ružička E, Schroeter ML, Jech R, Möller HE.   +10 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

DEVELOPMENT OF QUALITY CONTROL SAMPLE TO ASSESS SPECIFIC ACTIVITY OF ANTI-RABIES IMMUNOGLOBULIN OBTAINED FROM EQUINE BLOOD SERUM

Разработка и регистрация лекарственных средств, 2019
The paper contains the data on the development of quality control sample (QCS) for determination of specific activity of heterologous anti-rabies immunoglobulin in neutralization test on white mice.
E. G. Abramova, O. A. Lobovikova, I. V. Shul’gina, A. V. Komissarov, L. V. Savitskaya, S. V. Generalov, M. V. Galkina, Yu. K. Gavrilova, A. V. Kochkin, A. K. Nikiforov   +9 more
doaj  

Learning and discrimination through STDP in a top-down modulated associative memory

, 2006
This article underlines the learning and discrimination capabilities of a model of associative memory based on artificial networks of spiking neurons.
Mouraud, Anthony, Paugam-Moisy, Hélène
core   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optimization of Deuteron Irradiation of ¹⁷⁶Yb for Producing ¹⁷⁷Lu of High Specific Activity Exceeding 3000 GBq/mg. [PDF]

Molecules, 2023
Shao L.
europepmc   +1 more source

Radionuclide Specific Activity [PDF]

, 2020
openaire   +1 more source