Results 81 to 90 of about 639,854 (264)

Adaptation of Diverse Maize Germplasm to Spring Season Conditions in Northeast China

open access: yesAgronomy
Northeast China (NEC) is a major spring maize (Zea mays L.) growing belt, and the outputs substantially influence national grain production. However, the maize grain yield per unit area has little changes in recent years, partially due to the lack of ...
Yi Li   +14 more
doaj   +1 more source

Assessment of gene action and combining ability for fibre and yield contributing trais in interspecific and intraspecific hybrids of cotton

open access: yesCzech Journal of Genetics and Plant Breeding, 2018
Combining ability analysis was performed in order to identify high-yielding genotypes and hybrids. Six lines were crossed with three testers using a line × tester mating design. General combining ability (GCA) of parents, specific combining ability (SCA)
Sana MUNIR   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Concept of General and Specific Combining Ability in Relation to Diallel Crossing Systems [PDF]

open access: yesAustralian Journal of Biological Sciences, 1956
A detailed examination of the concept of combining ability in relation to diallel crossing systems is made. Eight different analyses aro presented. 'l'hese result from a consideration of four different diallel crossing systems together wit.h two alternative assumptions with regard to the sampling nature of tho experimental material. A numerical example
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Combining ability studies for yield and yield components trait in hybrid rice (Oryza sativa L.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2012
Fifty two hybrids were generated from crossing four CMS lines and thirteen restorer lines in line x tester design. Crosses along with parents were evaluated for yield and yield component traits during rabi, 2011 at RARS, Jagtial, Andhra Pradesh ...
P.V. Padmavathi, P.V. Satyanarayana , Lal Ahamed M.,Y. Ashoka Rani and V. Srinivasa Rao
doaj  

GENERAL AND SPECIFIC COMBINING ABILITY OF GROWTH PERFORMANCE ATTRIBUTES IN RABBITS [PDF]

open access: yesEgyptian Journal of Rabbit Science, 2021
Kariman Farg   +3 more
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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