Results 51 to 60 of about 13,372,123 (291)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effects of natural rock properties on cutting forces, specific energy and specific cutting energy by four-axis machine [PDF]
This study used a four-axis machine to investigate the processability of natural rocks and parameters affecting cutting forces (Cf), specific energy (Se) and specific cutting energy (Sc).
Erkan Özkan +3 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Summary Due to the lack of weed-specific designs in weeding equipment, this article conducted cutting experiments on one type of weed: Canadian goldenrod.
Ziyu Li +7 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
On Energy Assessment of Titanium Alloys Belt Grinding Involving Abrasive Wear Effects
Improved energy utilisation, precision, and quality are critical in the current trend of low-carbon green manufacturing. In this study, three abrasive belts were prepared at various wear stages and characterised quantitatively.
Mingcong Li +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Energy Efficiency in Natural Stone Cutting Process [PDF]
IEEE Energy 2030 Conference -- NOV 17-18, 2008 -- Atlanta, GAThe aim of this experimental study was to reduce electric energy consumption in marble cutting operation.
Nartkaya, M. +3 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Determination of specific energy in cutting process using diamond saw blade of natural stone
In this study, energy consumption of diamond saw blade, which is used for cutting natural stones, was examined as experimental. During the experiments, computer-controlled block cutting machine was used.
Ucun, Ismail +3 more
core +1 more source

