Results 61 to 70 of about 13,372,123 (291)
Nihon Kikai Gakkai ronbunshu, 2020 An evaluating equation to present the influence of thermal properties of workpiece and cutting tool on the cutting temperature is derived by the dimensional analysis.
Takashi UEDA +3 more
doaj +1 more source
Numerical simulation of induced cutting in deep coal [PDF]
Royal Society Open Science, 2019 Deep coal cutting is a hot research topic at present. In this paper, the cutting technology of three-drum shearer was proposed based on previous studies.
Si-fei Liu +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A review of the Energy Productivity Center's Least-Cost Energy Strategy study [PDF]
, 1981 The Mellon Institute's Energy Productivity Center (EPC) has recently completed a study asking the question, "How would the nation have provided energy services in 1978 if its capital stock had een reconfigured to be optimal for actual 1978 energy prices?"
Manove, Michael +2 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Jin'gangshi yu moliao moju gongcheng, 2017 Based on the existing energy consumption research, and according to the empirical relation between the material removal power and the no-load power and machining power of the machine tools, an empirical calculation model for cutting or grinding specific ...
YIN Hui +4 more
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Influence of the tool edge geometry on specific cutting energy at high-speed cutting [PDF]
, 2007 This paper presents specific cutting energy measurements as a function of the cutting speed and tool cutting edge geometry. The experimental work was carried out on a vertical CNC machining center with 7,500 rpm spindle rotation and 7.5 kW power ...
Coelho,Reginaldo T. +4 more
core +1 more source
Influence of pick working angle on cutting performance of auger miner’s aiguille
Advances in Mechanical Engineering, 2015 To study the influence of pick working angles on cutting performance of auger miner’s aiguille, aiguilles with different pick working angles were developed and their performance were tested on coal cutting test-bed.
Lin Fu +3 more
doaj +1 more source