Results 61 to 70 of about 8,084,296 (247)

Sectional domain specific languages

open access: yes, 2009
Nowadays, many problems are solved by using a domain specific language (DSL), i.e., a programming language tailored to work on a particular application domain.
W. Cazzola   +3 more
core   +1 more source

Specificity in LSP [PDF]

open access: yesIbérica, 2003
The defining feature of our field is the teaching and use of language for specific purposes. Not surprisingly, this has led to a debate over just how specific those purposes should be.
Thomas N. Huckin
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A Survey on Modeling Languages for Applications Hosted on Cloud-Edge Computing Environments

open access: yesApplied Sciences
In the field of edge-cloud computing environments, there is a continuous quest for new and simplified methods to automate the deployment and runtime adaptation to application lifecycle changes.
Ioannis Korontanis   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Domain-Specific Dictionary between Human and Machine Languages

open access: yesInformation
In the realm of artificial intelligence, knowledge graphs have become an effective area of research. Relationships between entities are depicted through a structural framework in knowledge graphs.
Md Saiful Islam, Fei Liu
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

De la notion de « langue appliquée » : vers une nécessaire autonomie

open access: yesMultilinguales, 2013
In this study we intend to demonstrate that applied languages are able to constitute a complete subfield of language didactics. However, until now, applied languages are often treated as Language​s Specialties (LS) or as Languages for Specific Purposes ...
M’hand Ammouden
doaj   +1 more source

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