Results 81 to 90 of about 187,630 (269)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Will we think in programming languages?

open access: yesActa Informatica Pragensia, 2012
Modern science commonly uses computer modelling. Thousands of scientific model are daily transformed to computers programs and tested. The transformation must overcome the gap between abstract human formal notation and low level semantics of contemporary
Jiří Fišer
doaj  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Languages for Specific Purposes and Integration of Scientific Knowledge

open access: yesСибирское юридическое обозрение, 2011
The author examines the emergence of language for specific purposes, its functions and features.
Galina Grigoreevna Babalova
doaj  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

THE U.S. FOREIGN LANGUAGE DEFICIT AND LANGUAGES FOR SPECIFIC PURPOSES [PDF]

open access: yesJournal of Languages for Specific Purposes, 2014
Within the framework of the U.S. foreign language deficit, the author addresses the case for Languages for Specific Purposes (LSP), and more specifically, Business Language Studies (BLS), through an examination of the relevant literature and building on ...
Kathleen Stein-Smith
doaj  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

TEACHING SIGN LANGUAGE FOR HEALTHCARE WITHIN A LANGUAGES FOR SPECIFIC PURPOSES FRAMEWORK [PDF]

open access: yesJournal of Languages for Specific Purposes, 2019
Languages for specific purposes is a subdiscipline of applied linguistics that looks at language learning and teaching for a specific education or training need.
Keren Cumberbatch
doaj  

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