Results 101 to 110 of about 1,814,894 (278)
Based on investigation of studies of reclamation survey by remote sensing both at home and abroad and demand analysis of process normalization for reclamation survey by remote sensing of North China Sea, the process of reclamation survey by remote ...
Haining ZHANG +6 more
doaj
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
The paper presents partial findings obtained during the study of external migration according to countries in a defined territorial unit and time period.
Milan Palát, Erich Maca
doaj +1 more source
Monitoring-Oriented Programming: A Tool-Supported Methodology for Higher Quality Object-Oriented Software [PDF]
This paper presents a tool-supported methodological paradigm for object-oriented software development, called monitoring-oriented programming and abbreviated MOP, in which runtime monitoring is a basic software design principle.
Chen, Feng +2 more
core
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
A Requirement Engineering Framework for Electric Motors Development
The applications using electric motors have increased in the last decade. Some of these applications encounter the need for tailor-made motors that must meet demanding requirements.
Christian A. Rivera +3 more
doaj +1 more source
RNA Binding: Getting Specific about Specificity [PDF]
Sequence-specific nucleic acid binding proteins do not recognize one sequence out of all possibilities; rather, they bind to many sequences with a range of affinities. In this issue of Cell Chemical Biology, Lin et al. (2016), describe the entire landscape of affinities between different RNA molecules and an RNA-binding protein, thus providing a ...
openaire +2 more sources
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Model checking deep neural networks: opportunities and challenges
Deep neural networks (DNNs) are extensively used in both current and future manufacturing, transportation, and healthcare sectors. The widespread use of neural networks in highly safety-critical applications has made it necessary to prevent catastrophic ...
Zohra Sbai, Zohra Sbai
doaj +1 more source

