Results 101 to 110 of about 1,814,894 (278)

The Study of Normalization for Reclamation Survey by Remote Sensing and Design of Specification of North China Sea

open access: yesHaiyang Kaifa yu guanli, 2022
Based on investigation of studies of reclamation survey by remote sensing both at home and abroad and demand analysis of process normalization for reclamation survey by remote sensing of North China Sea, the process of reclamation survey by remote ...
Haining ZHANG   +6 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Analysis of the population movement in the Czech Republic through external migration in the period 1993–2003

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2006
The paper presents partial findings obtained during the study of external migration according to countries in a defined territorial unit and time period.
Milan Palát, Erich Maca
doaj   +1 more source

Monitoring-Oriented Programming: A Tool-Supported Methodology for Higher Quality Object-Oriented Software [PDF]

open access: yes, 2004
This paper presents a tool-supported methodological paradigm for object-oriented software development, called monitoring-oriented programming and abbreviated MOP, in which runtime monitoring is a basic software design principle.
Chen, Feng   +2 more
core  

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A Requirement Engineering Framework for Electric Motors Development

open access: yesApplied Sciences, 2018
The applications using electric motors have increased in the last decade. Some of these applications encounter the need for tailor-made motors that must meet demanding requirements.
Christian A. Rivera   +3 more
doaj   +1 more source

RNA Binding: Getting Specific about Specificity [PDF]

open access: yesCell Chemical Biology, 2016
Sequence-specific nucleic acid binding proteins do not recognize one sequence out of all possibilities; rather, they bind to many sequences with a range of affinities. In this issue of Cell Chemical Biology, Lin et al. (2016), describe the entire landscape of affinities between different RNA molecules and an RNA-binding protein, thus providing a ...
openaire   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Model checking deep neural networks: opportunities and challenges

open access: yesFrontiers in Computer Science
Deep neural networks (DNNs) are extensively used in both current and future manufacturing, transportation, and healthcare sectors. The widespread use of neural networks in highly safety-critical applications has made it necessary to prevent catastrophic ...
Zohra Sbai, Zohra Sbai
doaj   +1 more source

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