Results 101 to 110 of about 2,598,347 (318)
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Friendships among non-kin individuals pose benefits related to survival and reproduction. However, dyadic relationships between any two individuals are not beneficial because of possibilities to exploit others. Selecting partners who are trustworthy is beneficial compared to forming bonds with exploitative partners.
openaire +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Sensitivity and Specificity of Ultrasonography in Diagnosis of Acute Appendicitis
BACKGROUND AND OBJECTIVE: Acute appendicitis is one of the most important urgent conditions of abdominal surgery, in which, proper and on-time diagnosis may decrease the unwanted complications.
A Mohammadi, F Khodabakhsh
doaj
STUDIES ON THE TUBERCULIN REACTION AND ON SPECIFIC HYPERSENSITIVENESS IN BACTERIAL INFECTION [PDF]
Hans Zinsser
openalex +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
Reassembling Formal Features in Articles by L1 Persian Learners of L2 English [PDF]
There has been considerable debate over what the sources of morphological variation in second language acquisition are. From among various hypotheses put forth on the topic, the feature reassembly hypothesis (Lardiere, 2005) assumes that it is the ...
Marjansadat Momenzadeh+1 more
doaj
Infantile gastro-enteritis with special reference to the specific serological type O55 B5 H6 (Betatype) ofBacterium coli [PDF]
Jennifer A. Smith+2 more
openalex +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
LVII.—On essential oils. Part III. Their specific refractive and dispersive energy [PDF]
J. H. Gladstone
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