Results 141 to 150 of about 4,525,804 (339)

The conformation of the nSrc specificity-determining loop in the Src SH3 domain is modulated by a WX conserved sequence motif found in SH3 domains

open access: yesFrontiers in Molecular Biosciences
Cellular signaling networks are modulated by multiple protein-protein interaction domains that coordinate extracellular inputs and processes to regulate cellular processes. Several of these domains recognize short linear motifs, or SLiMs, which are often
Frederick Longshore-Neate   +6 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A tuberculose multirresistente e a rainha vermelha - A rapidez do diagnóstico é decisiva Multi-drug resistant tuberculosis and the red queen - Diagnosis speed is crucial

open access: yesRevista Portuguesa de Pneumologia, 2007
A tuberculose multirresistente é uma ameaça importante ao controlo da tuberculose. Neste sentido, é fundamental o diagnóstico precoce da TBMR para adoptar as medidas mais adequadas.
João Costeira, Jaime Pina
doaj  

Diagnostic Performance of Artificial Intelligence in Rib Fracture Detection: Systematic Review and Meta-Analysis

open access: yesSurgeries
Artificial intelligence (AI) is a promising tool for diagnosing rib fractures. To date, only a few studies have quantified its performance. The objective of this systematic review was to assess the accuracy of AI as an independent tool for rib fracture ...
Marnix C. L. van den Broek   +3 more
doaj   +1 more source

A SIMPLIFIED METHOD FOR THE ESTIMATION OF TOTAL CHOLESTEROL IN SERUM AND DEMONSTRATION OF ITS SPECIFICITY

open access: hybrid, 1952
Liese L. Abell   +3 more
openalex   +1 more source

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