Results 141 to 150 of about 4,456,677 (340)

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Specific Friendships

open access: yes, 2018
Friendships among non-kin individuals pose benefits related to survival and reproduction. However, dyadic relationships between any two individuals are not beneficial because of possibilities to exploit others. Selecting partners who are trustworthy is beneficial compared to forming bonds with exploitative partners.
openaire   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Validación e implementación de GeneXpert MTB/RIF para diagnóstico de tuberculosis en Ecuador

open access: yesKasmera, 2019
: The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and ...
Ortiz-Jiménez, José Marcelo   +2 more
doaj  

Specificity of soil-borne pathogens on grain legumes [PDF]

open access: yes, 2004
Specificity of soil-borne legume pathogens on pea, lupin and faba bean is currently investigated in fields where grain legumes are intensively cultivated.
Bødker, Lars   +4 more
core  

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Robert Koch, Creation, and the Specificity of Germs [PDF]

open access: yes, 2010
Microbiology is dominated by evolution today. Just look at any text, journal article, or the topics presented at professional scientific meetings. Darwin is dominant. Microbiology is dominated by evolution today.
Gillen, Alan L.   +2 more
core   +1 more source

Specific situations

open access: yes, 2017
Ambulatory surgery can be carried out on a diabetic patient. By using a close organisational and technical approach, it minimises the risk of disequilibrium and allows the patient to return to his (her) previous way of life more quickly. Taking into account the context of this surgery with return home the same day, the objectives are to minimise any ...
Cheisson, Gaelle   +9 more
openaire   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

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