Results 61 to 70 of about 95,958 (315)
Cyclic Alternating Pattern Dynamics in Individuals at Risk for Developing Parkinson's Disease
Annals of Neurology, EarlyView.Objective The objective of this study was to investigate the differences in cyclic alternating patterns (CAP) metrics, a non‐rapid eye movement (NREM) sleep physiological rhythm, among recently diagnosed patients with Parkinson's disease (PD), and individuals at high and low risk for developing PD based on genetic and prodromal risk.
Andrew Dagay +5 more
wiley +1 more source
Development and task-based evaluation of a scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT [PDF]
arXiv, 2023 Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, traditional AC methods require the availability of a transmission scan, most often a CT scan.
arxiv
Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease
Annals of Neurology, EarlyView.Objective Although dopamine transporter (DaT) imaging is a valuable diagnostic biomarker, few studies have investigated its utility in objectively monitoring disease progression in patients with Parkinson's disease (PD). To date, no study has established a longitudinal relationship between the DaT signal decline and the motor symptom increase ...
Verena Dzialas +4 more
wiley +1 more source
Fluids and flows in brain cancer and neurological disorders
WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023 The different roles of fluids and flow in brain cancer (left) and Alzheimer's disease (right) into and out of the brain and within the interstitial spaces (insets). Abstract Interstitial fluid (IF) and cerebrospinal fluid (CSF) are an integral part of the brain, serving to cushion and protect the brain parenchymal cells against damage and aid in their ...
Peng Jin, Jennifer M. Munson
wiley +1 more source
Transformer-based Dual-domain Network for Few-view Dedicated Cardiac SPECT Image Reconstructions [PDF]
arXiv, 2023 Cardiovascular disease (CVD) is the leading cause of death worldwide, and myocardial perfusion imaging using SPECT has been widely used in the diagnosis of CVDs. The GE 530/570c dedicated cardiac SPECT scanners adopt a stationary geometry to simultaneously acquire 19 projections to increase sensitivity and achieve dynamic imaging.
arxiv
Advanced NanoBiomed Research, EarlyView.Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska +2 more
wiley +1 more source
A list-mode multi-energy window low-count SPECT reconstruction method for isotopes with multiple emission peaks [PDF]
arXiv, 2023 SPECT provides a mechanism to perform absorbed-dose quantification tasks for $\alpha$-particle radiopharmaceutical therapies ($\alpha$-RPTs). However, quantitative SPECT for $\alpha$-RPT is challenging due to the low number of detected counts, the complex emission spectrum, and other image-degrading artifacts.
arxiv
A list-mode OSEM-based attenuation and scatter compensation method for SPECT [PDF]
arXiv, 2020 Reliable attenuation and scatter compensation (ASC) is a prerequisite for quantification and beneficial for visual interpretation tasks in SPECT. In this paper, we develop a reconstruction method that uses the entire SPECT emission data, i.e. data in both the photopeak and scatter windows, acquired in list-mode format and including the energy attribute
arxiv
Technological Advances in SPECT and SPECT/CT Imaging
DiagnosticsSingle photon emission tomography/computed tomography (SPECT/CT) is a mature imaging technology with a dynamic role in the diagnosis and monitoring of a wide array of diseases. This paper reviews the technological advances, clinical impact, and future directions of SPECT and SPECT/CT imaging.
Yassine Bouchareb +8 more
openaire +3 more sources
Recent advances of nanomaterials in imaging liver fibrosis
BMEMat, EarlyView.Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui +11 more
wiley +1 more source