Results 91 to 100 of about 96,121 (306)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Some results on graph spectra

, 2002
This paper presents a variety of results on graph spectra. The number of main eigenvalues of a graph is shown to be equal to the rank of an associated matrix.
Hagos, Elias M., Elias M. Hagos
core   +1 more source

Spectral analysis of the wreath product of a complete graph with a cocktail party graph

Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2018
Graph products and the corresponding spectra are often studied in the literature. A special attention has been given to the wreath product of two graphs, which is derived from the homonymous product of groups.
Francesco Belardo, Matteo Cavaleri, Alfredo Donno   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Topological characteristics of IP networks [PDF]

, 2008
Topological analysis of the Internet is needed for developments on network planning, optimal routing algorithms, failure detection measures, and understanding business models.
Haddadi, H.
core  

Construction of Albertson Cospectral and Albertson Equienergetic Graphs Using Graph Operations

Journal of Mathematics
The energy of a graph is an invariant calculated as the sum of the absolute eigenvalues of its adjacency matrix. This concept extends to various types of energies derived from different graph-related matrices.
Jane Shonon Cutinha, Sabitha D’Souza, Swati Nayak   +2 more
doaj   +1 more source

Computation of the eigenvalues of complete signed graphs

Electronic Journal of Graph Theory and Applications
A signed graph Σ is the ordered pair (G,σ), where G=(V,E) is a finite simple graph, called the underlying graph, and σ: E(G) → {+1, -1} is a sign function or a signature of Σ. Let (K_n,σ) be a complete signed graph with n vertices. In this paper, we give
Shariefuddin Pirzada, Mir Riyaz Ul Rashid, Amir Rehman, Edy Tri Baskoro   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source