Results 51 to 60 of about 1,520 (199)
Exploring the Origin of Solar Energetic Electrons. II. Investigating Turbulent Coronal Acceleration
The Astrophysical JournalNonthermal particle acceleration in the solar corona is evident from both remote hard X-ray sources in the chromosphere and direct in situ detection in the heliosphere.
Ross Pallister +2 more
doaj +1 more source
Probabilistic Seismic Hazard Assessment of the Southwestern Region of Saudi Arabia
Applied SciencesIn relation to its rapid infrastructure expansion, exemplified by projects like the Najran Valley Dam or the rehabilitation of agricultural terraces, Saudi Arabia stands out among the Arabian Gulf nations.
Mohamed Arfa +4 more
doaj +1 more source
Advances in Civil Engineering, 2018 The efficiency of vector-valued intensity measures for predicting the seismic demand in gravity dams is investigated. The Folsom gravity dam-reservoir coupled system is selected and numerically analyzed under a set of two-hundred actual ground motions ...
Mohammad Alembagheri
doaj +1 more source
Accelerating spectral clustering on quantum and analog platforms
Academia QuantumWe introduce a novel hybrid quantum–analog algorithm to perform a graph clustering that exploits connections between the evolution of dynamical systems on graphs and the underlying graph spectra. This approach constitutes a new class of algorithms that combine emerging quantum and analog platforms to accelerate computations.
Xingzi Xu, Tuhin Sahai
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Journal of the Civil Engineering ForumSeismic response analysis is a key aspect in earthquake geotechnical engineering, as it provides important insights into the behavior of soils when exposedtoseismic forces.
Giovanny Dhebby Anggraini +5 more
doaj +1 more source