Results 241 to 250 of about 6,363,211 (303)

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

A Spectral Method of Characteristics for Hyperbolic Problems

SIAM Journal on Numerical Analysis, 1991
A spectral method is combined with a timestepping along the characteristics for numerical solution of first-order hyperbolic equations. Theorems about stability and convergence are proved. Numerical examples for one- and two-dimensional problems are given.
Endre Suli
exaly   +3 more sources

Spectral Characteristics of the Voices of Twins

Acta geneticae medicae et gemellologiae, 1963
SUMMARYA study is described in which the spectral similarities in the voices of monozygotic, dizygotic and non-twin controls is compared. The results are based on a statistical comparison of the differences between pairs of individuals at a number of spectral points.
M, ALPERT, R L, KURTZBERG, M, PILOT, A J, FRIEDHOFF   +3 more
openaire   +2 more sources

Spectral characteristics of acoustic cavitation

Ultrasonics, 1989
This paper reports on theoretical research into the dynamics, acoustic noise and noise spectrum of a single cavitation bubble affected by non-gradiental acoustic fields. It is shown that all the characteristic features of experimental acoustic cavitation spectra occur in the spectrum of a single bubble.
V I, Ilyichev, V L, Koretz, N P, Melnikov   +2 more
openaire   +2 more sources

Spectral Characteristics and Displacement Sensing of U-Shaped Single-Mode–Multimode–Single-Mode Fiber Structure [PDF]

Sensors
Xiaolei Bai, Chuan Tian
exaly   +2 more sources

Spectral characteristics of OWSS signal

IEEE Communications Letters, 2005
A recently reported signaling system called orthogonal wavelet spread spectrum (OWSS) is aimed at high speed WLANs. This letter discusses the generation and spectral properties of its basis pulses and the spectral characteristics of the transmit signal.
Dinesh Divakaran, Vijay K. Jain, Brent A. Myers   +2 more
openaire   +2 more sources