Results 61 to 70 of about 92,516 (310)

Lattice Boltzmann method for direct numerical simulation of turbulent flows [PDF]

, 2010
We present three-dimensional numerical simulations (DNS) of the Kida vortex flow, a prototypical turbulent flow, using a novel high-order lattice Boltzmann model.
A. G. TOMBOULIDES, S. S. CHIKATAMARLA, Tomboulides, A.G., Boulouchos, Konstantinos, K. B. BOULOUCHOS, Frouzakis, C.E., Boulouchos, K.B., C. E. FROUZAKIS, I. V. KARLIN, Karlin, Ilya, Chikatamarla, S.S., Karlin, I.V.   +11 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dynamic Analysis of Tapered Thin-Walled Beams Using Spectral Finite Element Method

Shock and Vibration, 2019
Tapered thin-walled structures have been widely used in wind turbine and rotor blade. In this paper, a spectral finite element model is developed to investigate tapered thin-walled beam structures, in which torsion related warping effect is included ...
Yiping Shen, Zhijun Zhu, Songlai Wang, Gang Wang   +3 more
doaj   +1 more source

A Study on the Vibration Analysis of Thick-Walled, Fluid-Conveying Pipelines with Internal Hydrostatic Pressure

Journal of Marine Science and Engineering, 2023
Pipelines are designed to carry seawater with hydrostatic pressure below sea level in the ship industry. Previously conducted studies have established the FSI (Fluid–Structure Interaction) equations for thin-walled, fluid-filled pipelines based on the ...
Hongzhen Zhu, Jianghai Wu
doaj   +1 more source

DOLFIN: Automated finite element computing

, 2009
We describe here a library aimed at automating the solution of partial differential equations using the finite element method. By employing novel techniques for automated code generation, the library combines a high level of expressiveness with efficient
Wells, G.N., Logg, Anders,, Logg, Anders
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Quadrilateral mesh optimisation method based on swarm intelligence optimisation

Scientific Reports
As oil and gas exploration advances, the growing complexity of geological conditions demands higher-quality quadrilateral meshes for spectral element method-based seismic simulations.
Fen Zhang, Jiuyun Tian, Panpan LV, Kaiyun Luo, Yonggu Huang, Shaohui Yang, Fei Deng   +6 more
doaj   +1 more source

The implementation of the mortar spectral element discretization of the heat equation with discontinuous diffusion coefficient

Boundary Value Problems, 2019
We propose to implement the mortar spectral elements discretization of the heat equation in a bounded two-dimensional domain with a piecewise continuous diffusion coefficient. The discretization on time is based on the Euler implicit method.
Mohamed Abdelwahed, Nejmeddine Chorfi
doaj   +1 more source