Results 71 to 80 of about 92,516 (310)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Archives of Mechanics, 2012 This paper concerns the Lattice Boltzmann Method (LBM) which has recently become alternative, computationally efficient tool to simulate a Newtonian fluid flow, especially in complex geometries.
W. Regulski, J. Szumbarski
doaj +1 more source
A priori error indicator in the transformation method for problems with geometric uncertainties [PDF]
, 2013 Version éditeur de cette publication à l'adresse suivante : http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6514655To solve stochastic problems with geometric uncertainties, one can transform the original problem in a domain with stochastic ...
Mac, Duc Hung +4 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
High-Order Methods Applied to Nonlinear Magnetostatic Problems
Mathematical and Computational Applications, 2019 This paper presents a comparison between two high-order modeling methods for solving magnetostatic problems under magnetic saturation, focused on the extraction of machine parameters.
Léo A. J. Friedrich +3 more
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An improved spectral decomposition flexibility perturbation method for finite element model updating
Advances in Mechanical Engineering, 2018 Finite element analysis is the most powerful tool to predict the behavior of a structure in engineering practice. Generally, the initial finite element model must be corrected with experimental data due to its complexity.
QW Yang, BX Sun, C Lu
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Adaptive numerical integration technique for the analysis of open planar circuits and antennas [PDF]
, 1997 This paper presents new adaptive integration technique in the spectral domain to speed up the impedance matrix calculation. This includes the adaptive truncation which limits the infinite integration into the finite computer resources and the adaptive ...
C. J. Railton +4 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Penalty resolution of the spectral element discretization of the time dependent Darcy equations
Boundary Value ProblemsThe time-dependent Darcy system, when discretized in time using the implicit Euler scheme and in space using the spectral element method, can be efficiently solved using the penalty method.
Nejmeddine Chorfi +2 more
doaj +1 more source