Results 61 to 70 of about 1,455,401 (342)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Treatment planning with a 2.5 MV photon beam for radiation therapy
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi+5 more
wiley +1 more source
On the complete integrability of the discrete Nahm equations
The discrete Nahm equations, a system of matrix valued difference equations, arose in the work of Braam and Austin on half-integral mass hyperbolic monopoles. We show that the discrete Nahm equations are completely integrable in a natural sense: to any
Murray, Michael K., Singer, Michael A.
core +1 more source
Iterative solution of a discrete axially symmetric potential problem [PDF]
The Dirichlet problem for the axially symmetric potential equation in a cylindrical domain is discretized by means of a five-point difference approximation. The resulting difference equation is solved by point or line iterative methods.
Boersma, J., Le Grand, P.
core +2 more sources
The influence of the electric polarization of hydrogen atoms on the red shift of its spectral lines [PDF]
The Lorentz oscillator system is studied to interpret the spectral lines of hydrogen atoms. The dielectric constant of this system is analyzed, which takes into account the electrical polarization of hydrogen atoms. This dielectric constant gives the red shift of the spectral line and the appearance of the optical spectrum dip.
arxiv
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Impact of flexible noise control (FNC) image processing parameters on portable chest radiography
Abstract There is a lack of understanding in the performance of flexible noise control (FNC) processing, which is used in digital radiography on a scanner vendor and has four parameters each involving multiple options. The aim of this study was to investigate the impact of FNC on portable chest imaging. An anthropomorphic chest phantom was imaged using
Krystal M. Kirby+6 more
wiley +1 more source
Modeling the near-infrared lines of O-type stars [PDF]
We use a grid of 30 line-blanketed unified stellar photosphere and wind models for O-type stars; computed with the code CMFGEN in order to evaluate its potential in the near-infrared spectral domain. The grid includes dwarfs, giants and supergiants.
de Koter, A.+3 more
core +2 more sources
Random sampling technique for ultra-fast computations of molecular opacities for exoplanet atmospheres [PDF]
Opacities of molecules in exoplanet atmospheres rely on increasingly detailed line-lists for these molecules. The line lists available today contain for many species up to several billions of lines. Computation of the spectral line profile created by pressure and temperature broadening, the Voigt profile, of all of these lines is becoming a ...
arxiv +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source