Results 61 to 70 of about 1,312,433 (296)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Electronic Spectral Functions for Quantum Hall Edge States

, 1996
We have evaluated wavevector-dependent electronic spectral functions for integer and fractional quantum Hall edge states using a chiral Luttinger liquid model.
A. Furusaki, A. H. MacDonald, A. H. MacDonald, A. H. MacDonald, A. H. MacDonald, A. M. Chang, B. I. Halperin, C. L. Kane, D. B. Mast, D. C. Glattli, F. D. M. Haldane, F. P. Milliken, G. D. Mahan, G. E. Andrews, H. J. Schulz, H. Maurey, I. Grodnensky, J. J. Palacios, J. P. Eisenstein, J. Smoliner, J. Sólyom, K. Moon, K. Moon, K. Schönhammer, M. Büttiker, M. Fabrizio, M. Franco, M. Wassermeier, P. Fendley, P. J. M. Peters, R. B. Laughlin, R. C. Ashoori, S. Giovanazzi, S. J. Allen, T. Demel, U. Zülicke, V. A. Volkov, V. J. Emery, W. Apel, X. G. Wen, X. G. Wen, X. G. Wen, Y. Oreg   +42 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Anti-Interference Spectral Confocal Sensors Based on Line Spot

Sensors
Spectral confocal displacement sensors are non-contact optoelectronic sensors widely utilized for their high accuracy, speed, and ability to measure diverse surfaces.
Bo Wang, Jiafu Li, Mingzhe Luo, Fengshuang Liang, Jiacheng Hu   +4 more
doaj   +1 more source

Microlensing in H1413+117 : disentangling line profile emission and absorption in a broad absorption line quasar

, 2010
On the basis of 16 years of spectroscopic observations of the four components of the gravitationally lensed broad absorption line (BAL) quasar H1413+117, covering the ultraviolet to visible rest-frame spectral range, we analyze the spectral differences ...
Angonin, Anguita, Anguita, B. Borguet, Barlow, Barlow, Becker, Belle, Bjorkman, Borguet, Borguet, Bradford, Chae, Chae, Chantry, Chelouche, Corbin, D. Hutsemékers, D. Sluse, Eigenbrod, Furlanetto, Gallagher, Gibson, Goicoechea, Goodrich, Goodrich, Hamann, Hutsemékers, Hutsemékers, Hutsemékers, Hutsemékers, Kayser, Kneib, Kuraszkiewicz, Lamy, Lewis, Lewis, Lutz, MacLeod, Magain, Magain, Markwardt, McIntosh, Monier, Murray, Nestor, Ogle, P. Riaud, Pei, Poindexter, Proga, Reichard, Remy, Richards, Saha, Scannapieco, Scannapieco, Schmidt, Schramm, Shakura, Silk, Sluse, Sluse, Surdej, T. Anguita, Turnshek, Turnshek, Voit, Weymann, Witt, Young, Zhou, Østensen   +72 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The Relativistic Fe Emission Line in XTE J1650-500 with BeppoSAX: Evidence for Black Hole Spin and Light Bending Effects?

, 2003
We report spectral results from three BeppoSAX observations of the black hole candidate XTE J1650-500 during its 2001/2002 outburst. We find strong evidence for the presence of a broad and strongly relativistic Fe emission line.
A. C. Fabian, Arnaud, Boella, Boella, Castro-Tirado, Dovčiak, Fabian, Fabian, Frontera, G. Miniutti, Groot, Guainazzi, Homan, Homan, J. M. Miller, Magdziarz, Markwardt, Martocchia, McClintock, Miller, Miller, Miller, Miller, Miniutti, Miniutti, Mitsuda, Méndez, Nandra, Parmar, Remillard, Revnivtsev, Reynolds, Reynolds, Rossi, Shih, Skibo, Tanaka, Tanaka, Taylor, Turner, Turner, Van Der Klis, Wijnands, Wilms, Yaqoob, Young   +45 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Determination of Tin by Spectral Lines with Different Sensitivity of Alternating Current Arc Emission Spectroscopy

Yankuang ceshi, 2013
Based on the advantages of simultaneous determination of multiple elements by using different spectral lines of Alternating Current Arc Emission Spectroscopy, samples with a large range of Sn contents were simultaneously determined by the major spectral ...
YU Yu, HE Zhen-yun, MAO Zhen-cai, WEI Yi, YUAN Xiu-ru, LIU Jiang-bin   +5 more
doaj