Results 81 to 90 of about 1,334,336 (314)
“N”-shaped Y/X coda spectral ratio observed for in-line-type OBS networks; S-net and ETMC: interpretation based on natural vibration of pressure vessel [PDF]
Kaoru Sawazaki, Takeshi Nakamura
openalex +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Synthesis of the Beryllium 3131A Spectral Region [PDF]
The Beryllium spectral region of the Sun, Procyon and 4 stars in the open cluster NGC6633 up to Teff = 7500K have been synthesised using ATLAS9 model atmospheres and the MOOG spectral synthesis program.
Ashwell, Johanna F. +2 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Vanishing lines in generalized Adams spectral sequences are generic
We show that in a generalized Adams spectral sequence, the presence of a vanishing line of fixed slope (at some term of the spectral sequence, with some intercept) is a generic property.Comment: 11 pages.
Hovey +5 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Bayesian Model Reconstruction Based on Spectral Line Observations
Spectral line observations encode a wealth of information. A key challenge, therefore, lies in the interpretation of these observations in terms of models to derive the physical and chemical properties of the astronomical environments from which they ...
Frederik De Ceuster +4 more
doaj +1 more source
On broad iron K-alpha lines in Seyfert 1 galaxies
The X-ray spectrum obtained by Tanaka et al from a long observation of the active galaxy MCG$-6-30-15$ shows a broad iron K$\alpha$ line skewed to low energies.
Brandt, W. N. +7 more
core +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source

