Results 51 to 60 of about 181,061 (267)
¹³C NMR metabolomics: applications at natural abundance. [PDF]
, 2014 (13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien +7 more
core +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Astrophysical Journal Supplement Series, 1978 A wavelength list of spectral lines between 1000 and 1940 A is presented for the solar flare that occurred on June 15, 1973. The spectra were recorded by the NRL spectrograph on Skylab. The spectral resolution is 0.06 A. Intensities, identifications, and estimates of line widths are given.
L. Cohen, U. Feldman, G. A. Doschek
openaire +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The chemical composition of a mild barium star HD202109
, 2003 We present the result of chemical abundances of a mild barium star HD202109 (zeta Cyg) determined from the analysis of spectrum obtained by using a 2-m telescope at the Peak Terskol Observatory and a high-resolution spectrometer with R=80,000, signal to ...
Galazutdinov, G. A. +5 more
core +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
PyEMILI: A New Generation Computer-aided Spectral Line Identifier
The Astrophysical Journal Supplement SeriesDeep high-dispersion spectroscopy of Galactic photoionized gaseous nebulae, mainly planetary nebulae and H ii regions, has revealed numerous emission lines.
Zhijun Tu +3 more
doaj +1 more source
Long-Term X-ray Spectral Variability in Seyfert 1 Galaxies
, 2003 Direct time-resolved spectral fitting has been performed on continuous RXTE monitoring of seven Seyfert 1 galaxies in order to study their broadband spectral variability and Fe K alpha variability characteristics on time scales of days to years ...
A. Markowitz +11 more
core +1 more source
Effects of NMR spectral resolution on protein structure calculation [PDF]
, 2013 Adequate digital resolution and signal sensitivity are two critical factors for protein structure determinations by solution NMR spectroscopy. The prime objective for obtaining high digital resolution is to resolve peak overlap, especially in NOESY ...
Güntert, Peter +3 more
core +3 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source