Results 31 to 40 of about 1,366,012 (305)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Maximizing analytical precision: exploring the advantages of ratiometric strategy in fluorescence, Raman, electrochemical, and mass spectrometry detection

Frontiers in Analytical Science, 2023
Ratiometric strategy are an invaluable method that helps to detect and quantify analytes. This approach relies on measuring changes in the ratio of two or more signals to improve the accuracy and sensitivity of the results.
Manivannan Madhu, S. Santhoshkumar, Wei-Bin Tseng, Wei-Lung Tseng, Wei-Lung Tseng   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Absorption mode FTICR mass spectrometry imaging [PDF]

, 2013
Fourier transform ion cyclotron resonance mass spectrometry offers the highest mass resolving power for molecular imaging experiments. This high mass resolving power ensures that closely spaced peaks at the same nominal mass are resolved for proper image
Konijnenburg, Marco, Heeren, Ron M. A., O’Connor, Peter B., Heeren, R.M.A., Smith, Donald Francis, Kilgour, David P. A., Kilgour, D.P.A., Konijnenburg, M., Smith, D.F., Sub Biomol.Mass Spectrometry & Proteom., O'Connor, P.B., Biomolecular Mass Spectrometry and Proteomics   +11 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Use of fluorescence imaging and spectrometry in detection of oral squamous cell carcinoma and oral potentially malignant disorders

Oral Oncology Reports
Objective: Changes in the autofluorescence of cancerous tissue in comparison to normal tissue due to alteration in the endogenous fluorophores and protein like NAD and FAD has been utilized in various oral cancer screening devices.
Vivek Nayyar, Pramila Thapa, Dalip Singh Mehta, Rahul Yadav, Krushna Bhatt, Varun Surya, Deepika Mishra   +6 more
doaj   +1 more source

Simple procedure for nutrient analysis of coffee plant with energy dispersive X-ray fluorescence spectrometry (EDXRF)

Scientia Agricola, 2013
Nutrient analysis is used to estimate nutrient content of crop plants to manage fertilizer application for sustained crop production. Direct solid analysis of agricultural and environmental samples by energy dispersive X-ray fluorescence spectrometry ...
Tiago Tezotto, José Laércio Favarin, Ana Paula Neto, Priscila Lupino Gratão, Ricardo Antunes Azevedo, Paulo Mazzafera   +5 more
doaj   +1 more source

X-ray Fluorescence Analysis of Waste Sm-Co Magnets: A Rational Approach

Recycling, 2023
Determination of the chemical composition of waste Sm-Co magnets is required for their efficient recycling. The non-stereotypical composition of said magnets makes an analysis extremely challenging.
Alexandra Alexandrovna Arkhipenko, Galina Evgenievna Marina, Marina Sergeevna Doronina, Natalya Alexandrovna Korotkova, Vasilisa Borisovna Baranovskaya   +4 more
doaj   +1 more source

Emprego da geração fotoquímica de vapor para análise de especiação e determinação de elementos-traço por espectrmetria atômica e de massa [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Este trabalho abrange duas técnicas distintas para a determinação de elementos-traço com ...
Quadros, Daiane Paula Cunha de
core