Results 31 to 40 of about 1,894,326 (313)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Detection of PFAS via surface-enhanced Raman scattering: Challenges and future perspectives

open access: yesSustainable Chemistry for the Environment, 2023
The upsurge in the alarm about the hazardous effects of one of the important emerging contaminants, Per- and polyfluoroalkyl substances (PFAS) are increasing in recent days.
Bhavya M.B.   +6 more
doaj   +1 more source

Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification

open access: yesScientific Reports, 2016
The mechanism of cell-penetrating peptides entry into cells is unclear, preventing the development of more efficient vectors for biotechnological or therapeutic purposes.
F. Illien   +7 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Foliar Elemental Analysis of Brazilian Crops via Portable X-ray Fluorescence Spectrometry

open access: yesSensors, 2020
Foliar analysis is very important for the nutritional management of crops and as a supplemental parameter for soil fertilizer recommendation. The elemental composition of plants is traditionally obtained by laboratory-based methods after acid digestion ...
Camila S. Borges   +7 more
doaj   +1 more source

Characterization of Bacillus subtilis Colony Biofilms via Mass Spectrometry and Fluorescence Imaging

open access: yesJournal of Proteome Research, 2016
Colony biofilms of Bacillus subtilis are a widely used model for studying cellular differentiation. Here, we applied matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) to examine cellular and molecular heterogeneity in B.
Tong Si   +5 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Innovation and Development for Atomic Fluorescence Spectrometry Analysis

open access: yesYankuang ceshi, 2013
Atomic fluorescence spectrometry (AFS) has such characteristics of chemical vapor separation and non dispersive optical system. It is one of the most successful analytical methods available to determine trace As, Sb, Bi, Hg, Se, Te and Ge elements ...
LI Gang, HU Si-xian, CHEN Lin-ling
doaj  

Geochemical Characteristics of Selenium in Surface Soil of Central Townships in Zhaojue County, Sichuan Province

open access: yesYankuang ceshi, 2022
BACKGROUND Selenium (Se) is one of the essential trace elements for humans, and an important way for humans to obtain and supplement selenium is by eating natural selenium-enriched agricultural products. The geochemical characteristics of selenium in the
ZHAO Chen   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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