Results 141 to 150 of about 105,942 (260)

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula   +4 more
wiley   +1 more source

Extending Serum IgG1 Antibody Repertoire Coverage Using DIA-PTCR. [PDF]

open access: yesJ Am Soc Mass Spectrom
Leuvenink RW   +4 more
europepmc   +1 more source

Steric modulation of nitric oxide photodissociation kinetics in iron–nitrosyl complexes

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Subtle steric modification within a pyridinophane ligand framework modulates nitric oxide photodissociation kinetics in iron–nitrosyl complexes. Structural and electrochemical analyses reveal that modest ligand‐environment variations are reflected in differences in NO photoreactivity.
Jisu Choe, Jaeheung Cho
wiley   +1 more source

A Step-by-Step Protocol From METASPACE to Biological Interpretation. [PDF]

open access: yesJ Mass Spectrom
Moreno-Pedraza A   +6 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

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