Results 31 to 40 of about 329,130 (249)

Metabolite Fingerprinting Based on ¹H-NMR Spectroscopy and Liquid Chromatography for the Authentication of Herbal Products

Molecules, 2022
Herbal medicines (HMs) are regarded as one of the traditional medicines in health care to prevent and treat some diseases. Some herbal components such as turmeric and ginger are used as HMs, therefore the identification and confirmation of herbal use are
Florentinus Dika Octa Riswanto, Anjar Windarsih, Endang Lukitaningsih, Mohamad Rafi, Nurrulhidayah A. Fadzilah, Abdul Rohman   +5 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Phytoconstituents profiling of indigenous herbal drugs and its in vitro microbial, in silico biological examination against Severe acute respiratory syndrome coronavirus 2

World Journal of Traditional Chinese Medicine
Background: Habb-E-Shifa, Hamdard Sualin, and Hamdard Joshanda traditional herbal medicines may promote host resistance against infection by bacteria, viruses, and fungi which are easily accessible at inexpensive with no complexity.
T H. Mohamed Ahadu Shareef, M Mohamed Divan Masood, Irfan Navabshan, M Saiyad Musthafa   +3 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Green synthesis of nickel oxide nanoparticles using Acacia nilotica leaf extracts and investigation of their electrochemical and biological properties

Journal of Taibah University for Science, 2023
Green synthesis of nanoparticles (NPs) has attracted the researcher's attention due to its rapid, cost-effective, sustainable and eco-friendly nature. Current studies were carried out to perform and investigate the green synthesis of NiO NPs with aqueous
Shabbir Hussain, Muazzam Ali Muazzam, Mahmood Ahmed, Muhammad Ahmad, Zeeshan Mustafa, Shahzad Murtaza, Jigar Ali, Muhammad Ibrar, Muhammad Shahid, Muhammad Imran   +9 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Synergistic Effects of Organic and Chemical Fertilizers on Microbial-Mediated Carbon Stabilization: Insights from Metagenomics and Spectroscopy

Agronomy
Fertilization management constitutes a critical determinant of agroecosystem productivity. Reasonable fertilization can increase the organic matter content in soil; however, the potential mechanism of how different fertilization regimes impact soil ...
Wei Wang, Yue Jiang, Shanshan Cai, Yumei Li, Juanjuan Qu, Lei Sun   +5 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Analytical Techniques for the Characterization and Quantification of Monoclonal Antibodies

Pharmaceuticals, 2023
Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are widely used in the identification and detection of cell makers, serum analytes, and pathogenic agents, and are remarkably used for the cure of autoimmune diseases ...
Hassan A. Alhazmi, Mohammed Albratty
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source