Results 101 to 110 of about 3,195,954 (330)

Focus on spectroscopy [PDF]

Physics Today, 1971
The usual Euler-Maclaurin expansion [1], [21 contains odd-order derivatives. The one which is proposed here contains only even-order derivatives.
openaire   +7 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Generation of 22-mJ, 2.0-ps Pulses from a 1-kHz Ho:YLF Regenerative Chirped Pulse Amplifier [PDF]

EPJ Web of Conferences
We report a CW-pumped Ho:YLF regenerative amplifier (RA) delivering pulses with 22.5-mJ energy and 2.0-ps duration at 1 kHz. The RA emitting at 2051 nm is broadband-seeded and implemented in a chirped pulse amplification system. © 2024 The Author(s)
Bock Martin, von Grafenstein Lorenz, Mero Mark, Nagy Tamas, Griebner Uwe   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Electronic Spectroscopy of Isolated DNA Polyanions

, 2018
In solution, UV-vis spectroscopy is often used to investigate structural changes in biomolecules (i.e., nucleic acids), owing to changes in the environment of their chromophores (i.e., the nucleobases).
Daly, Steven, Gabelica, Valérie, Porrini, Massimiliano, Rosu, Frederic   +3 more
core   +2 more sources

In situ and real-time ultrafast spectroscopy of photoinduced reactions in perovskite nanomaterials

Nature Communications
By employing two synchronized mode-locked femtosecond lasers and interferometric detection of the pump-probe spectra—referred to as asynchronous and interferometric transient absorption—we have developed a method for broad dynamic range and rapid data ...
Gi Rim Han, Mai Ngoc An, Hyunmin Jang, Noh Soo Han, JunWoo Kim, Kwang Seob Jeong, Tai Hyun Yoon, Minhaeng Cho   +7 more
doaj   +1 more source

Shock Waves in Laser-Induced Plasmas

Atoms, 2019
The production of a plasma by a pulsed laser beam in solids, liquids or gas is often associated with the generation of a strong shock wave, which can be studied and interpreted in the framework of the theory of strong explosion.
Beatrice Campanella, Stefano Legnaioli, Stefano Pagnotta, Francesco Poggialini, Vincenzo Palleschi   +4 more
doaj   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

The proton radius puzzle

, 2017
High-precision measurements of the proton radius from laser spectroscopy of muonic hydrogen demonstrated up to six standard deviations smaller values than obtained from electron-proton scattering and hydrogen spectroscopy. The status of this discrepancy,
Ahmed, M. Abdou, Amaro, F. D., Amaro, P., Antognini, A., Bigot, E. -O. Le, Biraben, F., Cardoso, J. M. R., Carvalho, M. L., Covita, D. S., Dax, A., Dhawan, S., Diepold, M., Fernandes, L. M. P., Franke, B., Galtier, S., Giesen, A., Gouvea, A. L., Graf, T., Guerra, M., Götzfried, J., Haack, J., Hildebrandt, M., Hänsch, T. W., Indelicato, P., Julien, L., Kirch, K., Knecht, A., Knowles, P., Kottmann, F., Krauth, J. J., Liu, Y. -W., Lopes, J. A. M., Ludhova, L., Machado, J., Monteiro, C. M. B., Mulhauser, F., Nebel, T., Nez, F., Pohl, R., Rabinowitz, P., Rapisarda, E., Santos, J. M. F. dos, Santos, J. P., Schaller, L. A., Schuhmann, K., Schwob, C., Szabo, C. I., Taqqu, D., Veloso, J. F. C. A., Voss, A., Weichelt, B., Willig, M.   +51 more
core   +1 more source