Results 101 to 110 of about 3,143,049 (329)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Generation of 22-mJ, 2.0-ps Pulses from a 1-kHz Ho:YLF Regenerative Chirped Pulse Amplifier [PDF]

EPJ Web of Conferences
We report a CW-pumped Ho:YLF regenerative amplifier (RA) delivering pulses with 22.5-mJ energy and 2.0-ps duration at 1 kHz. The RA emitting at 2051 nm is broadband-seeded and implemented in a chirped pulse amplification system. © 2024 The Author(s)
Bock Martin, von Grafenstein Lorenz, Mero Mark, Nagy Tamas, Griebner Uwe   +4 more
doaj   +1 more source

The proton radius puzzle

, 2017
High-precision measurements of the proton radius from laser spectroscopy of muonic hydrogen demonstrated up to six standard deviations smaller values than obtained from electron-proton scattering and hydrogen spectroscopy. The status of this discrepancy,
Ahmed, M. Abdou, Amaro, F. D., Amaro, P., Antognini, A., Bigot, E. -O. Le, Biraben, F., Cardoso, J. M. R., Carvalho, M. L., Covita, D. S., Dax, A., Dhawan, S., Diepold, M., Fernandes, L. M. P., Franke, B., Galtier, S., Giesen, A., Gouvea, A. L., Graf, T., Guerra, M., Götzfried, J., Haack, J., Hildebrandt, M., Hänsch, T. W., Indelicato, P., Julien, L., Kirch, K., Knecht, A., Knowles, P., Kottmann, F., Krauth, J. J., Liu, Y. -W., Lopes, J. A. M., Ludhova, L., Machado, J., Monteiro, C. M. B., Mulhauser, F., Nebel, T., Nez, F., Pohl, R., Rabinowitz, P., Rapisarda, E., Santos, J. M. F. dos, Santos, J. P., Schaller, L. A., Schuhmann, K., Schwob, C., Szabo, C. I., Taqqu, D., Veloso, J. F. C. A., Voss, A., Weichelt, B., Willig, M.   +51 more
core   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Array detection enables large localization range for simple and robust MINFLUX

Light: Science & Applications
The MINFLUX concept significantly improves the localization properties of single-molecule localization microscopy (SMLM) by overcoming the limit imposed by the fluorophore’s photon counts.
Eli Slenders, Sanket Patil, Marcus Oliver Held, Alessandro Zunino, Giuseppe Vicidomini   +4 more
doaj   +1 more source

Shock Waves in Laser-Induced Plasmas

Atoms, 2019
The production of a plasma by a pulsed laser beam in solids, liquids or gas is often associated with the generation of a strong shock wave, which can be studied and interpreted in the framework of the theory of strong explosion.
Beatrice Campanella, Stefano Legnaioli, Stefano Pagnotta, Francesco Poggialini, Vincenzo Palleschi   +4 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

In situ and real-time ultrafast spectroscopy of photoinduced reactions in perovskite nanomaterials

Nature Communications
By employing two synchronized mode-locked femtosecond lasers and interferometric detection of the pump-probe spectra—referred to as asynchronous and interferometric transient absorption—we have developed a method for broad dynamic range and rapid data ...
Gi Rim Han, Mai Ngoc An, Hyunmin Jang, Noh Soo Han, JunWoo Kim, Kwang Seob Jeong, Tai Hyun Yoon, Minhaeng Cho   +7 more
doaj   +1 more source

Temperature Dependences of Single Dye-Molecules Zero-Phonon Line Widths in a Broad Range of Low Temperatures

EPJ Web of Conferences, 2015
In the present work the individual temperature dependences of zero-phonon spectral line widths of single tetra-tert-butylterrylene dye-molecules in polyisobutylene were measured in a broad range of low temperatures (from 20 K up to 67 K).
Eremchev I. Yu., Gorshelev A.A., Karimullin K.R., Naumov A.V.   +3 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source