Results 81 to 90 of about 4,620,546 (371)

Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR

Nature Communications, 2018
The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto, Deni Mance, Tessa Sinnige, Mark Daniëls, Markus Weingarth, Marc Baldus   +5 more
doaj   +1 more source

Soliton absorption spectroscopy

, 2010
We analyze optical soliton propagation in the presence of weak absorption lines with much narrower linewidths as compared to the soliton spectrum width using the novel perturbation analysis technique based on an integral representation in the spectral ...
A. Biswas, E. Sorokin, G. P. Agrawal, I. T. Sorokina, J. Mandon, K. E. Oughstun, N. N. Akhmediev, S. A. Akhmanov, V. Kalashnikov, V. L. Kalashnikov, V. S. Butylkin   +10 more
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Evaluating pathological levels of intracellular cholesterol through Raman and surface-enhanced Raman spectroscopies

Scientific Reports
Versatile methods for the quantification of intracellular cholesterol are essential for understanding cellular physiology and for diagnosing disorders linked to cholesterol metabolism.
Enrico Baria, Caterina Dallari, Francesco Mattii, Francesco Saverio Pavone, Caterina Credi, Riccardo Cicchi, Amelia Morrone, Claudia Capitini, Martino Calamai   +8 more
doaj   +1 more source

Wide-field mid-infrared single-photon upconversion imaging

Nature Communications, 2022
The authors present a simple yet effective solution to dramatically boost the performances of an upconversion imaging system, which leads to unprecedented mid-infrared imaging features with large field of view, single-photon sensitivity and a MHz-level ...
Kun Huang, Jianan Fang, Ming Yan, E Wu, Heping Zeng   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

QCD spectroscopy [PDF]

Nuclear Physics B - Proceedings Supplements, 1994
Plenary talk at Lattice 93, 18 pages of ...
openaire   +2 more sources

Ultrafast photoinduced C-H bond formation from two small inorganic molecules

Nature Communications
The formation of carbon-hydrogen (C-H) bonds via the reaction of small inorganic molecules is of great significance for understanding the fundamental transition from inorganic to organic matter, and thus the origin of life. Yet, the detailed mechanism of
Zhejun Jiang, Hao Huang, Chenxu Lu, Lianrong Zhou, Shengzhe Pan, Junjie Qiang, Menghang Shi, Zhengjun Ye, Peifen Lu, Hongcheng Ni, Wenbin Zhang, Jian Wu   +11 more
doaj   +1 more source

Electron-nuclear correlated multiphoton-route to Rydberg fragments of molecules

Nature Communications, 2019
Rydberg atoms can be created from photoexcitation of molecules using intense ultrafast laser pulses. Here the authors use a coincidence detection of electrons, ion and excited Rydberg atoms and their energy sharing to reveal the general mechanism of ...
Wenbin Zhang, Xiaochun Gong, Hui Li, Peifen Lu, Fenghao Sun, Qinying Ji, Kang Lin, Junyang Ma, Hanxiao Li, Junjie Qiang, Feng He, Jian Wu   +11 more
doaj   +1 more source

Mid-infrared single-photon 3D imaging

Light: Science & Applications, 2023
Active mid-infrared (MIR) imagers capable of retrieving three-dimensional (3D) structure and reflectivity information are highly attractive in a wide range of biomedical and industrial applications.
Jianan Fang, Kun Huang, E Wu, Ming Yan, Heping Zeng   +4 more
doaj   +1 more source