Results 101 to 110 of about 3,250,375 (315)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A critical analysis of some of the arguments for the illegitimacy of rational investigation in religion [PDF]
Kom: Časopis za Religijske Nauke, 2018 The permissibility of rational investigation into matters of religion is a topic that has always been a subject of debate among Muslim scholars. It is even possible to categorize the various sects within the Islamic world based upon their view regarding ...
Shiraz Husain Agha
doaj
Quantum Corrected Non-Thermal Radiation Spectrum from the Tunnelling Mechanism
Galaxies, 2015 The tunnelling mechanism is today considered a popular and widely used method in describing Hawking radiation. However, in relation to black hole (BH) emission, this mechanism is mostly used to obtain the Hawking temperature by comparing the probability ...
Subenoy Chakraborty +2 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Effects of Destriping Errors on Estimates of the CMB Power Spectrum
, 2004 Destriping methods for constructing maps of the Cosmic Microwave Background (CMB) anisotropies have been investigated extensively in the literature. However, their error properties have been studied in less detail.
Bartolo +27 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Partial chord diagrams and matrix models
, 2017 In this article, the enumeration of partial chord diagrams is discussed via matrix model techniques. In addition to the basic data such as the number of backbones and chords, we also consider the Euler characteristic, the backbone spectrum, the boundary ...
Andersen, Jørgen Ellegaard +4 more
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Baryonic Symmetries in AdS4/CFT3: An Overview
Advances in High Energy Physics, 2011 Global symmetries play an important role in classifying the spectrum of a gauge theory. In the context of the AdS/CFT duality, global baryon-like symmetries are specially interesting.
Diego Rodriguez-Gomez
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