Results 91 to 100 of about 227,399 (278)

"The Great Near." Mondi possibili in The Princess Steel di W.E.B. DuBois

open access: yesIperstoria, 2016
W.E.B. Du Bois’s short storyThe Princess Steel(c. 1908) is a significant example of proto-Afrofuturist speculative fiction functioning as a powerful allegory on the origins of modern capitalistic industry.
Adriano Elia
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

After Speculative Realism

open access: yesDas Questões, 2023
Bensusan, Hilan   +1 more
openaire   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Reparative Realism in ‘Dry Ground Burning’

open access: yesArts
This article investigates the reparative politics of resistance at the heart of the production model and formal strategies developed by Joana Pimenta and Adirley Queirós in the film Dry Ground Burning [Mato Seco em Chamas] (2022).
Andrew Philip
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Eco-Delirium: Realism in Environmental Excess

open access: yesOpen Philosophy
This article describes “Eco-Delirium” as a historically situated theory of realism arising from the environmental crisis of the late-Cold War. Challenging the claims that postmodernism exhausted realism or made post-factual relativism possible, it argues
Dutta Ritam, Banerjee Indranil
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

THE END OF WHAT? PHENOMENOLOGY VS. SPECULATIVE REALISM

open access: yes, 2021
Phenomenology has recently come under attack from propo-nents of speculative realism. In this paper, I present and assess the criticism, and argue that it is either superficial and sim-plistic or lacks ...
Zahavi, Dan
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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