Results 91 to 100 of about 59,319 (299)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Knowledge and process in Whitehead’s philosophy of organism
Pensamiento. Revista de Investigación e Información Filosófica, 2014 The aim of this article is to expound the whiteheadian conception of knowledge as a process. It requires explaining previously the core of his metaphysics, known as the «speculative scheme».
Alfonso Gómez Fernández
doaj
"The Great Near." Mondi possibili in The Princess Steel di W.E.B. DuBois
Iperstoria, 2016 W.E.B. Du Bois’s short storyThe Princess Steel(c. 1908) is a significant example of proto-Afrofuturist speculative fiction functioning as a powerful allegory on the origins of modern capitalistic industry.
Adriano Elia
doaj +1 more source
Perdita by Hilary Scharper [PDF]
, 2014 Review of Perdita by Hilary ...
Bartley, Nicole
core +1 more source
Metaphor and Theological Realism [PDF]
, 2014 In this paper, I argue that there are indispensable and irreducible metaphors in religious language and that this does not threaten a realist interpretation of religion.
Sebastian, Gäb
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
DELEUZE’S CRITIQUE OF REPRESENTATION BETWEEN POST-STRUCTURALISM AND SPECULATIVE REALISM
Zbornik radova Filozofskog fakulteta u Splitu, 2018 Gilles Deleuze’s thought is uniquely placed at the interface of post-structuralism and the speculative/ontological turn which marked the humanities in general and continental philosophy in particular at the beginning of the twenty-first century.
Dubravka Dulibić-Paljar
doaj
Fear appeal construction in the Daily Mail Online:a critical discourse analysis of ‘Prime Minister Corbyn and the 1000 days that destroyed Britain’ [PDF]
, 2017 The rhetorical fear appeal is a technique of political communication that seeks to elicit an emotional response in receivers with the intention of provoking them to political action desired by the rhetor.
Panay, Andrew
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source