Results 91 to 100 of about 1,155 (253)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Buildings are not Processes: A Disagreement with Latour and Yaneva
Ardeth, 2017 The classic and traditional source on actor-network theory and architecture is a co-authored and well-know 2008 piece by Bruno Latour and Albena Yaneva («Give Me a Gun and I Will Make All Buildings Move»: An Ant’s View of Architecture).
Graham Harman
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Speculative Realism and Other Heresies
, 2014 This paper is a presentation of Speculative Realism that provides a brief summary of the most important protagonist’s positions: Quentin Meillassoux, Ray Brassier, Graham Harman and Iain Hamilton Grant. It includes a short history of this tendency starting from the Goldsmith workshop in April 2007 and mentioning more recent strategies and approaches ...
openaire +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
OBJECT-ORIENTED FEMINISM IN THE POSTHUMAN ENVIRONMENT
Вісник Харківського національного університету імені В.Н. Каразіна. Серія Філософія, філософські перипетіїThe article’s narrative begins by considering the negative attitude of women philosophers, particularly feminist philosophers, towards speculative realism (hereinafter referred to as SR) and object-oriented ontology (hereinafter referred to as OOO). This
Nataliia Zahurska
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Routledge Open ResearchIn recent years, extinction has become something of a buzzword used to portray the state of consciousness of the epoch. Its definition as a concept, however, heavily oscillates between naturalistic, speculative, ethical and critical connotations. The aim
Gregorio Tenti
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source