Results 81 to 90 of about 2,130 (284)

Icebound Modernity: The Shipwreck as Metaphor in Dan Simmons’ The Terror

open access: yesAmerican, British and Canadian Studies Journal, 2019
In this article, I seek to present a “metaphorology” of the shipwreck through a literary example. As Hans Blumenberg has noted, the shipwreck has served as a metaphor for the contingency of human existence in Western culture.
Lovasz Adam
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Knowledge and process in Whitehead’s philosophy of organism

open access: yesPensamiento. Revista de Investigación e Información Filosófica, 2014
The aim of this article is to expound the whiteheadian conception of knowledge as a process. It requires explaining previously the core of his metaphysics, known as the «speculative scheme».
Alfonso Gómez Fernández
doaj  

The argument from facticity: reassessing realism in Sartre’s early philosophy

open access: yesHumanities & Social Sciences Communications
This paper argues that Jean-Paul Sartre’s early philosophy—above all Being and Nothingness—advances a distinctive and insufficiently examined form of realism.
Christos Kalpakidis
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

DELEUZE’S CRITIQUE OF REPRESENTATION BETWEEN POST-STRUCTURALISM AND SPECULATIVE REALISM

open access: yesZbornik radova Filozofskog fakulteta u Splitu, 2018
Gilles Deleuze’s thought is uniquely placed at the interface of post-structuralism and the speculative/ontological turn which marked the humanities in general and continental philosophy in particular at the beginning of the twenty-first century.
Dubravka Dulibić-Paljar
doaj  

"The Great Near." Mondi possibili in The Princess Steel di W.E.B. DuBois

open access: yesIperstoria, 2016
W.E.B. Du Bois’s short storyThe Princess Steel(c. 1908) is a significant example of proto-Afrofuturist speculative fiction functioning as a powerful allegory on the origins of modern capitalistic industry.
Adriano Elia
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Aesthetics in the 21st Century [PDF]

open access: yes, 2014
Ever since the turn of the century aesthetics has steadily gained momentum as a central field of study across the disciplines. No longer sidelined, aesthetics has grown in confidence.

core  

Realism Today? [PDF]

open access: yes, 2018
While much attention has been paid in recent years to philosophical realism—especially to speculative realism—and its implications for contemporary art, this roundtable purposefully aims to broaden the discussion to account for more “traditional” and art
Khatib, Sami   +4 more
core   +1 more source

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