Results 81 to 90 of about 227,399 (278)

Icebound Modernity: The Shipwreck as Metaphor in Dan Simmons’ The Terror

American, British and Canadian Studies Journal, 2019
In this article, I seek to present a “metaphorology” of the shipwreck through a literary example. As Hans Blumenberg has noted, the shipwreck has served as a metaphor for the contingency of human existence in Western culture.
Lovasz Adam
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

DELEUZE’S CRITIQUE OF REPRESENTATION BETWEEN POST-STRUCTURALISM AND SPECULATIVE REALISM

Zbornik radova Filozofskog fakulteta u Splitu, 2018
Gilles Deleuze’s thought is uniquely placed at the interface of post-structuralism and the speculative/ontological turn which marked the humanities in general and continental philosophy in particular at the beginning of the twenty-first century.
Dubravka Dulibić-Paljar
doaj  

Speculative Realisms and Religion

Calenda, 2013
The Journal ThéoRèmes is devoting a special issue to this presence of the religious question in various philosophical studies related to “Speculative realism” or even “object-oriented ontologies”, in order both to deepen the internal understanding of this question, and to develop critical approaches. We welcome contributions from a range of disciplines
openaire   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

The argument from facticity: reassessing realism in Sartre’s early philosophy

Humanities & Social Sciences Communications
This paper argues that Jean-Paul Sartre’s early philosophy—above all Being and Nothingness—advances a distinctive and insufficiently examined form of realism.
Christos Kalpakidis
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Sonic Living: Space and the Speculative in James Baldwin’s “Sonny’s Blues”

James Baldwin Review, 2018
In a 1961 interview with the journalist Studs Terkel, James Baldwin offered a riveting assessment of Bessie Smith’s “Backwater Blues.” “It’s a fantastic kind of understatement,” Baldwin tells Terkel.
Maleda Belilgne
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Speculative Tate

, 2014
Speculative Realism is a term that is used to describe an approach that attempts to consider art, politics, nature and thought beyond the confines of human finitude.
Pendrell, Luke
core