Results 101 to 110 of about 392,381 (314)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

A look at the ethnic-racial issues in the Math history presentations presented by the 2018 PNLD medical education Mathematical books

open access: yesEducação Matemática Debate, 2019
This text consists of studies carried out in the Graduate Program in Mathematical Education of the Federal University of Mato Grosso do Sul (PPGEdumat / UFMS) and is part of the research line "Curriculum and Mathematical Education".
Alan Pereira Manoel   +1 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Comparative study of the selected methods of laryngeal tone determination

open access: yesArchives of Acoustics, 2014
Laryngeal tone (pitch), understood as fundamental frequency of the voice ($F_0$), is one of the most important features in the field of acoustic studies of the speech signal.
W. Wszołek, M. Kłaczyński
doaj  

Speech synthesis, Speech simulation and speech science

open access: yes, 2002
Speech synthesis research has been transformed in recent years through the exploitation of speech corpora - both for statistical modelling and as a source of signals for concatenative synthesis.
Huckvale, M
core  

PRODUCTION AND PERCEPTUAL ANALYSIS OF SPEECH PRODUCED IN NOISE [PDF]

open access: yes, 2010
When exposed to noise, speakers modify the way they speak, possibly in an effort to maintain intelligible communication. These modifications are collectively referred to as the Lombard effect.
LU, YOUYI
core  

Glottal source estimation from coded telephone speech using a deep neural network [PDF]

open access: yes, 2017
In speech analysis, the information about the glottal source is obtained from speech by using glottal inverse filtering (GIF). The accuracy of state-of-the-art GIF methods is sufficiently high when the input speech signal is of high-quality (i.e., with ...
Manu Airaksinen   +5 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The acoustic and electroglottographic methods of determination the vocal folds vibration fundamental frequency

open access: yesArchives of Acoustics, 2014
There are many methods of measuring fundamental frequency of vocal folds’ vibrations. The mentioned function can be estimated in several ways, either through internal measurements (optical methods) or external measurements (the acoustic analysis of the
Wiesław Wszołek   +2 more
doaj  

Analysis of speech production real-time MRI

open access: yes, 2018
Recent advances in real-time magnetic resonance imaging (RT-MRI) have made it possible to study the anatomy and dynamic motion of the vocal tract during speech production with great detail.
Narayanan, Shrikanth,   +21 more
core   +1 more source

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